HPLC Determination of Ciclopirox on Newcrom A Column

HPLC Method for Ciclopirox on Newcrom A by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of Ciclopirox.

Ciclopirox is a prescription medication with the chemical formula C12H17NO2. It is used to treat topical fungal infections on skin, nails, and scalp. It is available in a variety of forms from shampoo, to nail lacquer, to cream.

Ciclopirox can be retained and analyzed using the Newcrom A stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a perchloric acid buffer. Detection is performed using UV.

Condition
Column Newcrom A, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN – 45%
Buffer HClO4 – 0.2%
Flow Rate 1.0 ml/min
Detection UV 300 nm

Description
Class of Compounds Drug, Synthetic antifungal agent
Analyzing Compounds Ciclopirox

 

Application Column

Newcrom A

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Ciclopirox
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.