Ethyl cyanoacetate

Ethyl cyanoacetate structural formula

CAS Number105-56-6
Molecular FormulaC5H7NO2
Molecular Weight113.116
InChI KeyZIUSEGSNTOUIPT-UHFFFAOYSA-N
LogP-0.0670
Synonyms
  • Ethyl cyanoacetate
  • Acetic acid, 2-cyano-, ethyl ester
  • 105-56-6
  • Acetic acid, cyano-, ethyl ester
  • (Ethoxycarbonyl)acetonitrile
  • ACETATE, CYANO-, ETHYL
  • Acetic acid, 2-cyano-, ethyl ester
  • ACETIC ACID, CYANO-, ETHYLESTER
  • cianoacetato de etilo
  • CYANESSIGSAEURE-AETHYLESTER
  • Cyanoacetate d'ethyle
  • Cyanoacetic acid ethyl ester
  • Cyanoacetic ester
  • Ethyl 2-cyanoacetate
  • Ethyl cyanacetate
  • Ethyl cyanoethanoate
  • Ethyl ?-cyanoacetate
  • Ethylcyanacetat
  • Malonic acid ethyl ester nitrile
  • MALONIC ETHYL ESTER NITRILE
  • NSC 8844
  • UN 2666
  • BRN 0605871
  • EINECS 203-309-0
  • Cyanacetate ethyle
  • Estere cianoacetico
  • Ethylester kyseliny kyanoctove
  • UNII-X9N006U0F8

Applications:

Separation of Ethyl cyanoacetate on Newcrom R1 HPLC column

May 16, 2018
Separation of Ethyl cyanoacetate on Newcrom R1 HPLC column

Ethyl cyanoacetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Ethyl cyanoacetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.