Dimethyl malonate

Dimethyl malonate structural formula

CAS Number108-59-8
Molecular FormulaC5H8O4
Molecular Weight132.116
InChI KeyBEPAFCGSDWSTEL-UHFFFAOYSA-N
LogP-0.0500
Synonyms
  • Dimethyl malonate
  • Dimethyl propanedioate
  • Propanedioic acid, dimethyl ester
  • 108-59-8
  • Propanedioic acid, dimethyl ester
  • 1,3-Dimethyl propanedioate
  • Dimethyl 1,3-propanedioate
  • Dimethyl propanedioate
  • Dimethylmalonat
  • Malonate de dimethyle
  • malonato de dimetilo
  • Malonic acid, dimethyl ester
  • MALONSAEURE-DIMETHYLESTER
  • Methyl malonate
  • NSC 620046
  • PROPANEDIOATE, DIMETHYL
  • Propanedioic acid dimethyl ester
  • Propanedioic acid, 1,3-dimethyl ester
  • EINECS 203-597-8
  • UNII-EM8Y79998C

Applications:

Separation of Dimethyl malonate on Newcrom R1 HPLC column

February 16, 2018
Separation of Dimethyl malonate on Newcrom C18 HPLC column

Dimethyl malonate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Dimethyl malonate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.