di-tert-Butyl-4-hydroxymethyl phenol

di-tert-Butyl-4-hydroxymethyl phenol structural formula

CAS Number88-26-6
Molecular FormulaC15H24O2
Molecular Weight236.355
InChI KeyHNURKXXMYARGAY-UHFFFAOYSA-N
LogP3.74
Synonyms
  • di-tert-Butyl-4-hydroxymethyl phenol
  • 2,6-Di-tert-butyl-4-(hydroxymethyl)phenol
  • Benzenemethanol, 3,5-bis(1,1-dimethylethyl)-4-hydroxy-
  • 88-26-6
  • 4-06-00-06080
  • Antioxidant 754
  • BHT alcohol
  • 3,5-Bis(1,1-dimethylethyl)-4-hydroxybenzenemethanol
  • BRN 2052291
  • Butylated hydroxymethylphenol
  • 3,5-Di-t-butyl-4-hydroxybenzyl alcohol
  • 2,6-Di-t-butyl-4-hydroxymethylphenol
  • EINECS 201-815-6
  • alpha-Hydroxy-2,6-di-tert-butyl-p-cresol
  • Ionox 100 antioxidant
  • NSC 159133
  • UNII-46ND6GQI48

Applications:

Separation of di-tert-Butyl-4-hydroxymethyl phenol on Newcrom R1 HPLC column

February 19, 2018
Separation of di-tert-Butyl-4-hydroxymethyl phenol on Newcrom C18 HPLC column

di-tert-Butyl-4-hydroxymethyl phenol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
di-tert-Butyl-4-hydroxymethyl phenol
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.