Clofibric acid

Clofibric acid structural formula

CAS Number882-09-7
Molecular FormulaC10H11ClO3
Molecular Weight214.650
InChI KeyTXCGAZHTZHNUAI-UHFFFAOYSA-N
LogP2.57
Synonyms
  • Clofibric acid
  • 2-(4-Chlorophenoxy)-2-methylpropanoic acid
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-
  • 882-09-7
  • 2-(p-Chlorophenoxy)-2-methylpropionic acid
  • Propanoic acid, 2-(4-chlorophenoxy)-2-methyl-
  • (p-Chlorophenoxy)isobutyric acid
  • 2-(4-Chlorophenoxy)-2-methylpropanoic acid
  • 2-(4-Chlorophenoxy)-2-methylpropionic acid
  • 2-(p-Chlorophenoxy)-2-methylpropanoic acid
  • 2-(p-Chlorophenoxy)isobutyric acid
  • 2-(p-Chlorphenoxy)-2-methylpropionsaure
  • 2-[(4-Chlorophenyl)oxy]-2-methylpropionic acid
  • 4-Chlorophenoxyisobutyric acid
  • acide 2-(p-chlorophenoxy)-2-methylpropionique
  • acido 2-(p-clorofenoxi)-2-metilpropionico
  • Arteriohom
  • Chlorfibrinic acid
  • Chlorofibrinic acid
  • Chlorophibrinic acid
  • Clofibrate free acid
  • Clofibrilic acid
  • Clofibrin
  • Clofibrinic acid
  • NSC 1149
  • Propionic acid, 2-(p-chlorophenoxy)-2-methyl-
  • Regadrin
  • Regulipid
  • ?-(4-Chlorophenoxy)isobutyric acid
  • ?-(4-Chlorophenoxy)-?-methylpropionic acid
  • ?-(p-Chlorophenoxy)isobutyric acid
  • Acetic acid, (p-chlorophenoxy)dimethyl-
  • Acidum chlorphibricum
  • BRN 1874067
  • alpha-(p-Chlorophenoxy)isobutyric acid
  • p-(2,4-Chlorophenoxy)isobutyric acid
  • alpha-(4-Chlorophenoxy)isobutyric acid
  • 4-(Chlorophenoxy)isobutyric acid
  • EINECS 212-925-9
  • alpha-(4-(Chlorphenoxy)-2-methylpropionsaeure
  • Acide clofibrique
  • Acido clofibrico
  • Acidum clofibricum
  • UNII-53PF01Q249
  • NSC-1149
  • 4-CPIB
  • Acide (p-chlorophenoxy)-2 methyl-2 propionique
  • CPIB
  • Chlorfibrinic acid
  • Clofibrinsaeure
  • PCIB
  • PCPIB
  • alpha-(4-chlorophenoxy)-alpha-methylpropionic acid
  • alpha-(p-chlorophenoxy)isobutyric acid

Applications:

Separation of Clofibric acid on Newcrom R1 HPLC column

February 16, 2018
Separation of Clofibric acid on Newcrom C18 HPLC column

Clofibric acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Clofibric acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.