beta-Propiolactone

beta-Propiolactone structural formula

CAS Number57-57-8
Molecular FormulaC3H4O2
Molecular Weight72.064
InChI KeyVEZXCJBBBCKRPI-UHFFFAOYSA-N
LogP-0.804
Synonyms
  • beta-Propiolactone
  • Oxetan-2-one
  • 2-Oxetanone
  • 57-57-8
  • Propiolactone
  • 5-17-09-00003
  • 2-Oxetanone
  • 1,3-Propiolactone
  • 3-Hydroxypropionic acid lactone
  • 3-Propanolide
  • 3-Propiolactone
  • Betaprone
  • BETA-PROPIOLACTON
  • Hydracrylic acid, ?-lactone
  • NSC 21626
  • Propanoic acid, 3-hydroxy-, ?-lactone
  • Propanolide
  • Propiolacton
  • propiolactona
  • ?-Propiolactone
  • ?-Propionolactone
  • BRN 0001360
  • Caswell No. 709
  • EINECS 200-340-1
  • EPA Pesticide Chemical Code 010901
  • Propanoic acid, 3-hydroxy-, beta-lactone
  • Propionic acid, 3-hydroxy-, beta-lactone
  • beta-Proprolactone
  • Propiolactonum
  • Propiolattone
  • UNII-6RC3ZT4HB0
  • 3-hydroxypropionic acid beta-lactone
  • beta-Propiolakton
  • beta-lactone hydracrylic acid
  • beta-propanoic acid lactone
  • beta-propiolactone
  • beta-propionolactone
  • betapron
  • hydracrylic acid beta-lactone

Applications:

Separation of beta-Propiolactone on Newcrom R1 HPLC column

May 16, 2018
Separation of beta-Propiolactone on Newcrom R1 HPLC column

beta-Propiolactone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
beta-Propiolactone
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.