Beclazone

Beclazone structural formula

CAS Number5534-09-8
Molecular FormulaC28H37ClO7
Molecular Weight521.050
InChI KeyKUVIULQEHSCUHY-XYWKZLDCSA-N
LogP4.10
Synonyms
  • Beclazone
  • (11beta,16beta)-9-Chloro-11-hydroxy-16-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl dipropanoate
  • Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11beta,16beta)-
  • 5534-09-8
  • Beclomethasone dipropionate
  • Pregna-1,4-diene-3,20-dione, 9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)-, (11?,16?)-
  • 17,21-dipropionate de 9-chloro-11?-hydroxy-16?-methylpregna-1,4-diene-3,20-dione
  • 17,21-dipropionato de 9-cloro-11?-hidroxi-16?-metilpregna-1,4-dieno-3,20-diona
  • 9-Chlor-11?-hydroxy-16?-methylpregna-1,4-dien-3,20-dion-17,21-dipropionat
  • 9-chloro-11?-hydroxy-16?-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
  • 9?-Chloro-16?-methylprednisolone 17,21-dipropionate
  • Aerobec
  • Aldecin
  • Aldecin AQ nasal
  • Anceron
  • Beclacin
  • Beclate
  • Beclazone 250
  • Beclazone 50
  • Beclomet
  • Beclometasone 17,21-dipropionate
  • Beclometasone dipropionate
  • BECLOMETHASONE 17,21-DIPROPIONATE
  • Beclomethasone 17?,21-dipropionate
  • Beclotide
  • Beclotide 100
  • Becloval
  • Beclovent
  • Beclovent Inhaler
  • Becodisks
  • Beconase
  • Beconase AQ
  • Becotide
  • Belchlorhinol
  • Belcoforte
  • Belcomet
  • Clenil A
  • Entyderma
  • Inalone O
  • Inalone R
  • Korbutone
  • Pregna-1,4-diene-3,20-dione, 9-chloro-11?,17,21-trihydroxy-16?-methyl-, 17,21-dipropionate
  • Propaderm
  • Propaderm Forte
  • Rino-Clenil
  • Sanasthmax
  • Sanasthmyl
  • Sanasthymyl
  • Topster
  • Vancenase
  • Vancenase AQ
  • Vanceril
  • Vanceril DS
  • Ventolair
  • Becloforte
  • Benconase
  • Clenil-A
  • EINECS 226-886-0
  • Alanase
  • Aldecina
  • Aldecine
  • Atomase
  • Beclocort Nasel
  • Beclomet Nasal
  • Beclorhinol
  • Becloturmant
  • Respocort
  • Rhino Clenil
  • Rhinosol
  • Turbinal
  • Vanceril Double Strength
  • UNII-5B307S63B2
  • Menaderm
  • Beclometasone dipropionato
  • (11beta,16beta)-9-chloro-11-hydroxy-16-methyl-17,21-bis(1-oxopropoxy)pregna-1,4-diene-3,20-dione
  • 9-chloro-11beta-hydroxy-16beta-methylpregna-1,4-diene-3,20-dione 17,21-dipropionate
  • 9-chloro-16beta-methyl-11beta,17,21-trihydroxypregna-1,4-diene-3,20-dione 17,21-dipropionate
  • 34135-07-4

Applications:

Separation of Beclazone on Newcrom R1 HPLC column

February 16, 2018
Separation of Beclazone on Newcrom C18 HPLC column

Beclazone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Beclazone
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.