alpha-Lipoic acid amide

alpha-Lipoic acid amide structural formula

CAS Number940-69-2
Molecular FormulaC8H15NOS2
Molecular Weight205.331
InChI KeyFCCDDURTIIUXBY-UHFFFAOYSA-N
LogP1.51
Synonyms
  • alpha-Lipoic acid amide
  • 5-(1,2-Dithiolan-3-yl)pentanamide
  • 1,2-Dithiolane-3-pentanamide
  • 940-69-2
  • 5-19-07-00238
  • BRN 0122470
  • EINECS 213-375-2
  • Thioctic acid amide
  • Ticolin
  • (+-)-1,2-Dithiolane-3-pentanamide
  • (+-)-1,2-Dithiolane-3-valeramide
  • (+-)-Thioctic acid amide
  • alpha-Lipoamide
  • DL-alpha-Lipoic acid amide
  • DL-6,8-Thioctamide
  • NSC 90787
  • Thioctic amide
  • UNII-Q1GT04827L
  • 1,2-dithiolane-3-pentanamide
  • 5-(1,2-Dithiolan-3-yl)-pentanamide
  • 5-(1,2-Dithiolan-3-yl)valeramide
  • 5-(1,2-dithiolan-3-yl)pentanamide
  • 5-(3-dithiolanyl)pentanamide
  • 5-(dithiolan-3-yl)pentanamide
  • 5-(dithiolan-3-yl)valeramide
  • DL-lipoamide
  • Dl-6-Thioctic amide
  • Lipamide
  • Lipoamid
  • Lipoicin
  • Lipozyme
  • Lypoaran
  • Pathoclon
  • Thioami
  • Thioctamid
  • Thioctamide
  • Thioctic acid amide (jan)
  • Thiotomin
  • Ticolin
  • alpha-Lipoate
  • alpha-Lipoic acid
  • lipoacin
  • vitamin N
  • lipoamide

Applications:

Separation of alpha-Lipoic acid amide on Newcrom R1 HPLC column

February 16, 2018
Separation of alpha-Lipoic acid amide on Newcrom C18 HPLC column

alpha-Lipoic acid amide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
alpha-Lipoic acid amide
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.