.alpha.-Ketoisocaproic acid

.alpha.-Ketoisocaproic acid structural formula

CAS Number816-66-0
Molecular FormulaC6H10O3
Molecular Weight130.144
InChI KeyBKAJNAXTPSGJCU-UHFFFAOYSA-N
LogP0.531
Synonyms
  • .alpha.-Ketoisocaproic acid
  • 4-Methyl-2-oxopentanoic acid
  • Pentanoic acid, 4-methyl-2-oxo-
  • 816-66-0
  • Pentanoic acid, 4-methyl-2-oxo-
  • 2-keto-4-Methylvaleric acid
  • 2-Ketoisocaproic acid
  • 2-Oxo-4-methylpentanoic acid
  • 2-Oxo-4-methylvaleric acid
  • 2-Oxoisocaproic acid
  • 2-Oxoleucine
  • 4-Methyl-2-oxopentanoic acid
  • 4-Methyl-2-oxovaleriansaure
  • 4-methyl-2-oxovaleric acid
  • Acide 4-methyl-2-oxovalerique
  • acido 4-metil-2-oxovalerico
  • Ketoleucine
  • VALERIC ACID, 4-METHYL-2-OXO-
  • ?-Ketoisocaproic acid
  • ?-Ketoisocapronic acid
  • ?-Oxoisocaproic acid
  • EINECS 212-435-5
  • UNII-4GUJ8AH400
  • 2-Keto-4-Methylvalerate
  • 2-Ketoisocaproate
  • 2-Oxo-4-methylpentanoate
  • 2-Oxo-4-methylvalerate
  • 2-Oxo-4-methylvaleric acid
  • 2-keto-4-methyl-valeric acid
  • 4-Methyl-2-oxo-Valerate
  • 4-Methyl-2-oxo-Valeric acid
  • 4-Methyl-2-oxopentanoate
  • 4-methyl-2-oxo-pentanoic acid
  • 4-methyl-2-oxopentanoic acid
  • Ketoisocaproate
  • Ketoisocaproic acid
  • Methyloxovalerate
  • Methyloxovaleric acid
  • Oxoisocaproate
  • Oxoisocaproic acid
  • a-Ketoisocaproate
  • a-Ketoisocaproic acid
  • a-Ketoisocapronate
  • a-Ketoisocapronic acid
  • a-Oxoisocaproate
  • a-Oxoisocaproic acid
  • alpha-Keto-isocaproate
  • alpha-Keto-isocaproic acid
  • alpha-Ketoisocaproate
  • alpha-Ketoisocapronate
  • alpha-Ketoisocapronic acid
  • alpha-Oxoisocaproate
  • alpha-Oxoisocaproic acid
  • alpha-ketoisocaproic acid

Applications:

Separation of .alpha.-Ketoisocaproic acid on Newcrom R1 HPLC column

February 19, 2018
Separation of .alpha.-Ketoisocaproic acid on Newcrom C18 HPLC column

.alpha.-Ketoisocaproic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
.alpha.-Ketoisocaproic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.