Aloe-emodin structural formula

CAS Number481-72-1
Molecular FormulaC15H10O5
Molecular Weight270.240
  • Aloe-emodin
  • 1,8-Dihydroxy-3-(hydroxymethyl)anthracene-9,10-dione
  • 9,10-Anthracenedione, 1,8-dihydroxy-3-(hydroxymethyl)-
  • 481-72-1
  • 4-08-00-03578
  • BRN 2059062
  • 1,8-Dihydroxy-3-(hydroxymethyl)-9,10-anthracenedione
  • 1,8-Dihydroxy-3-hydroxymethylanthraquinone
  • EINECS 207-571-7
  • Emodine
  • 3-Hydroxymethylchrysazin
  • NSC 38628
  • 3-(Hydroxymethyl)chrysazin
  • Aloeemodin
  • Rhabarberone
  • Aloe emodin


Separation of Aloe-emodin on Newcrom R1 HPLC column

February 16, 2018
Separation of Aloe-emodin on Newcrom C18 HPLC column

Aloe-emodin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: or by phone: 847-229-2629.