4,6-Diaminotoluene-2-sulphonic acid

4,6-Diaminotoluene-2-sulphonic acid structural formula

CAS Number85153-45-3
Molecular FormulaC7H10N2O3S
Molecular Weight202.231
InChI KeyAFUHLZJMSIKUOK-UHFFFAOYSA-N
LogP-2.45
Synonyms
  • 4,6-Diaminotoluene-2-sulphonic acid
  • 3,5-Diamino-2-methylbenzene-1-sulfonic acid
  • Benzenesulfonic acid, 3,5-diamino-2-methyl-
  • 85153-45-3
  • EINECS 285-826-1

Applications:

Separation of 4,6-Diaminotoluene-2-sulphonic acid on Newcrom R1 HPLC column

2018-05-17
Separation of 4,6-Diaminotoluene-2-sulphonic acid on Newcrom R1 HPLC column

4,6-Diaminotoluene-2-sulphonic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Analytes:
4,6-Diaminotoluene-2-sulphonic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.

Newcrom R1

The Newcrom columns are a family of reverse phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 columns are standard reverse phase columns with octyldecyl silane chains (C18) attached to porous silica. We have also designed a line of Newcrom R1 columns with a new outer design. This column and corresponding adapter entirely eliminate the need for any high-pressure fittings or tubing as well as minimizing all possible dead volumes. Furthermore, if a leak ever occurs in the high-pressure column inlet, the mobile phase is contained within the column adapter (no external leakage).

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