2-Hydroxy-3-methylbenzoic acid

2-Hydroxy-3-methylbenzoic acid structural formula

CAS Number83-40-9
Molecular FormulaC8H8O3
Molecular Weight152.150
InChI KeyWHSXTWFYRGOBGO-UHFFFAOYSA-N
LogP2.86
Synonyms
  • 2-Hydroxy-3-methylbenzoic acid
  • Benzoic acid, 2-hydroxy-3-methyl-
  • 83-40-9
  • Benzoic acid, 2-hydroxy-3-methyl-
  • 4-10-00-00601
  • Acidum hydroxitoluicum
  • BRN 2086811
  • EINECS 201-473-8
  • 2-Hydroxy-m-toluic acid
  • NSC 17561
  • Acide hydroxytoluique
  • Acido 3-ossi-5-metil-benzoico
  • Acido hidroxitoluico
  • Acido ortocresotinico
  • Acidum hydroxytoluicum
  • UNII-ZH3HEY032H
  • 2,3-Cresotate
  • 2,3-Cresotic acid
  • 2,3-Cresotinate
  • 2,3-Cresotinic acid
  • 2-Hydroxy-3-methyl-benzoate
  • 2-Hydroxy-3-methylbenzoate
  • 2-Hydroxy-m-toluate
  • 2-Hydroxy-m-toluic acid
  • 2-hydroxy-3-methyl-benzoic acid
  • 3-Cresotinate
  • 3-MS
  • 3-Methyl-2-hydroxybenzoate
  • 3-Methyl-2-hydroxybenzoic acid
  • 3-Methylsalicylate
  • 3-Methylsalicylic acid
  • 3-Methylsalicylsaeure
  • 3-methylsalicylate
  • Cresotic acid
  • Cresotinic acid
  • Homosalicylic acid
  • Hydroxytoluic acid
  • Hydroxytoluylsaeure
  • beta-Cresotinate
  • beta-Cresotinic acid
  • o-Cresotic acid
  • o-Cresotinic acid
  • o-Homosalicylic acid

Applications:

Separation of 2-Hydroxy-3-methylbenzoic acid on Newcrom R1 HPLC column

May 16, 2018
Separation of 2-Hydroxy-3-methylbenzoic acid on Newcrom R1 HPLC column

2-Hydroxy-3-methylbenzoic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2-Hydroxy-3-methylbenzoic acid
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.