1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester

1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester structural formula

CAS Number6413-10-1
Molecular FormulaC8H14O4
Molecular Weight174.196
InChI KeyXWEOGMYZFCHQNT-UHFFFAOYSA-N
LogP1.16
Synonyms
  • 1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester
  • Ethyl (2-methyl-1,3-dioxolan-2-yl)acetate
  • 6413-10-1
  • 5-19-07-00231
  • BRN 0130164
  • EINECS 229-114-0
  • Ethyl acetoacetate 3-ethylene acetal
  • Ethyl acetoacetate ethylene glycol ketal
  • Ethyl acetoacetate ethylene ketal
  • Ethyl 3-oxobutyrate ethylene ketal
  • Ethylacetoacetate ethyleneglycol ketal
  • Fructone
  • 2-Methyl-1,3-dioxolane-2-acetic acid ethyl ester
  • NSC 6537
  • UNII-G5EXI4NID0
  • 1021149-30-3

Applications:

Separation of 1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester on Newcrom R1 HPLC column

February 16, 2018
Separation of 1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester on Newcrom C18 HPLC column

1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
1,3-Dioxolane-2-acetic acid, 2-methyl-, ethyl ester
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.