| CAS Number | 698-87-3 |
|---|---|
| Molecular Formula | C9H12O |
| Molecular Weight | 136.19 |
| InChI Key | WYTRYIUQUDTGSX-UHFFFAOYSA-N |
| LogP | 2 |
| Synonyms |
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Applications:
HPLC Chiral Separation of 1-phenyl-2-propanol on Cyralis CM Column
June 22, 2026
HPLC Method for Analysis of 1-Phenyl-2-propanol on Cyralis CM Column by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of 1-Phenyl-2-propanol.
1-phenyl-2-propanol is a chiral secondary alcohol with the chemical formula C9H12O. It is primarily used in chemical research as well as as a fragrance. It has a sweet scent with a honey-like undertone. You can find detailed UV spectra of 1-Phenyl-2-propanol and information about its various lambda maxima by visiting the following link.
This application describes a normal-phase chiral HPLC method for the separation of 1-Phenyl-2-propanol enantiomers using SIELC’s Cyralis CM chiral column. Cyralis CM is a cellulose-based chiral stationary phase (CSP) designed for enantiomeric separations, optical purity testing, chiral impurity analysis, and stereoisomer characterization in pharmaceutical, chemical, agrochemical, and fine chemical applications. For best results, the sample should be prepared fresh for analysis.
1-Phenyl-2-propanol can be retained and analyzed using the Cyralis CM stationary phase column. The analysis utilizes an isocratic method with a mobile phase consisting of Hexane and Ethanol. Detection is performed using UV.
Condition
| Column | Cyralis CM, 4.6 x 250 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | Hexane/Ethanol- 99/1% |
| Flow Rate | 1.0 mL/min |
| Detection | UV 250 nm |
| Resolution | 1.64 |
Description
| Class of Compounds | Alcohol |
| Analyzing Compounds | 1-Phenyl-2-propanol |
Application Column
Cyralis CM
Column Diameter: 4.6 mm
Column Length: 250 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Uv-Vis Spectrum of 1-Phenyl-2-propanol
February 23, 2026
Access the UV-Vis Spectrum SIELC Library
If you are looking for optimized HPLC method to analyze 1-Phenyl-2-propanol check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
