Separation of Sodium and Potassium Ions on Newcrom AH Column

HPLC Method for Sodium, Potassium on Newcrom AH by SIELC Technologies 

 

Sodium Ions, Na+, are crucial for regulating fluid balance, transporting nutrients, and generating electrical signals within a body.

Potassium ions, K+, are essential for cell function. They work as charge carriers inside animal cells to create the membrane. Imbalance of potassium can lead to debilitating health problems, but consumption of it through a diet can help regulate the negative effects of sodium on blood flow.

Sodium and potassium ions can be separated on a mixed-mode Newcrom AH column with a simple isocratic mobile phase of water, acetonitrile (ACN) and methanesulfonic acid.  It can be detected using a conductivity detector.

Condition
Column Newcrom AH, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 50/50%
Buffer Methanesulfonic acid  – 10 mM
Flow Rate 1.0 ml/min
Detection Conductivity

 

Description
Class of Compounds Hydrophilic, Metal, Ion
Analyzing Compounds Sodium, Potassium

 

 

Application Column

Newcrom AH

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Potassium
Sodium
Application Detection:
Conductivity Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.