| CAS Number | 24634-61-5 |
|---|---|
| Molecular Formula | C6H7KO2 |
| Molecular Weight | 150.219 |
| InChI Key | CHHHXKFHOYLYRE-STWYSWDKSA-M |
| LogP | 0.650 |
| Synonyms |
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Applications:
HPLC Method for Separation of Ketoconazole and Potassium Sorbate on Primesep B Column
February 7, 2023
HPLC Method for Separation of Ketoconazole and Potassium Sorbate on Primesep B by SIELC Technologies
Separation type: Liquid Chromatography Mixed-mode
Ketoconazole, also known as Nizoral, is an antifungal compound used to treat dandruff and is commonly available as a shampoo. Ketoconazole can be retained, analyzed, and separated from Potassium sorbate on a Primesep B reverse-phase column using a gradient analytical method with a mobile phase consisting of Acetonitrile (MeCN), water, and Sulfuric acid as the ionic modifier. This analysis method can be UV detected at 200 nm with high resolution and peak symmetry.
High Performance Liquid Chromatography (HPLC) Method for Analysis of Ketoconazole and Potassium Sorbate
Condition
| Column | Primesep B, 4.6 x 150 mm, 5 µm, 100 A |
| Mobile Phase | Gradient MeCN – 10-50%, 10 min |
| Buffer | H2SO4 – 0.2% |
| Flow Rate | 1.0 ml/min |
| Detection | UV 200, 250 nm |
| Peak Retention Time | 6.31, 8.12 min |
Description
| Class of Compounds | Drug |
| Analyzing Compounds | Potassium sorbate, Sodium sorbate, Ketoconazole |
Application Column
Primesep B
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Potassium sorbate
Sodium sorbate
HPLC Method for Separation of Finasteride, Minoxidil and Potassium sorbate on Primesep 100 Column
February 3, 2023
HPLC Method for Separation of Finasteride, Minoxidil and Potassium sorbate on Primesep 100 by SIELC Technologies
Separation type: Liquid Chromatography Mixed-mode
Finasteride, also known as Proscar or Propecia, is a popular oral medication used to prevent hair loss and treat enlarged prostates (also known as benign prostatic hyperplasia, BPH). Minoxidil is another drug used to treat male pattern hair loss, as well as high blood pressure, and can be taken both orally or topically. Potassium Sorbate is a popular preservative used in a wide variety of foods, wines, and personal-care products. These 3 compounds can be retained, separated, and analyzed on a mixed-mode Newcrom BH column with a mobile phase consisting of water, Acetonitrile (MeCN), and sulfuric acid (H2SO4). This analytical method can be UV detected at 225 nm with high resolution and peak symmetry. The retention times and elution order of these compounds can be modified by altering the relative concentrations of MeCN and H2SO4.
High Performance Liquid Chromatography (HPLC) Method for Analysis of Finasteride, Minoxidil and Potassium sorbate
Condition
| Column | Primesep 100, 4.6 x 150 mm, 5 µm, 100 A |
| Mobile Phase | MeCN/H2O – 50/50% |
| Buffer | H2SO4 |
| Flow Rate | 1.0 ml/min |
| Detection | UV 225 nm |
| Peak Retention Time |
Description
| Class of Compounds | Drug |
| Analyzing Compounds | Finasteride, Minoxidil, Potassium sorbate |
Application Column
Primesep 100
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Minoxidil
Potassium sorbate
HPLC Method for Analysis of Potassium Sorbate on Newcrom BH Column
May 10, 2022
Potassium Sorbate is a popular preservative used in a wide variety of foods, wines, and personal-care products. Potassium Sorbate can be retained and analyzed on a mixed-mode Newcrom BH column with a mobile phase consisting of water, Acetonitrile (MeCN), and Sulfuric acid (H2SO4). This analytical method can be UV detected at 210 nm with high resolution and peak symmetry.
Application Column
Newcrom BH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsSorbic acid
Separation of Potassium sorbate on Newcrom R1 HPLC column
February 19, 2018
Potassium sorbate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options