Deoxycorticosterone acetate

Deoxycorticosterone acetate structural formula

CAS Number56-47-3
Molecular FormulaC23H32O4
Molecular Weight372.506
InChI KeyVPGRYOFKCNULNK-ACXQXYJUSA-N
LogP3.08
Synonyms
  • Deoxycorticosterone acetate
  • 3,20-Dioxopregn-4-en-21-yl acetate
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
  • 56-47-3
  • DOCA
  • 4-08-00-02195
  • Pregn-4-ene-3,20-dione, 21-(acetyloxy)-
  • 11-Deoxycorticosterone 21-acetate
  • 11-Deoxycorticosterone, acetate
  • 11-Desoxycorticosterone acetate
  • 21-Acetoxy-3,20-diketopregn-4-ene
  • 21-Acetoxypregn-4-en-3,20-dione
  • 21-Acetoxypregn-4-ene-3,20-dione
  • 21-Acetyloxypregn-4-ene-3,20-dione
  • 21-Hydroxypregn-4-ene-3,20-dione 21-acetate
  • 21-Hydroxypregn-4-ene-3,20-dione acetate
  • 4-Pregnene-3,20-dione 21-acetate
  • 4-Pregnene-3,20-dione-21-ol acetate
  • acetate de desoxycortone
  • acetato de desoxicortona
  • Bio-Corten
  • Cortacet
  • Cortate
  • Cortenil
  • Cortesan
  • Cortexone acetate
  • Cortifar
  • Cortigen
  • Cortinaq
  • Cortiron
  • Cortivis
  • Cortixyl
  • Decorten
  • Decosteron
  • Decosterone
  • Decostrate
  • Deoxycorticosterone 21-acetate
  • Deoxycortone acetate
  • Descorterone
  • Descotone
  • Desoxycorticosterone acetate
  • Desoxycortonacetat
  • desoxycortone acetate
  • DOC acetate
  • Dorcostrin
  • Doxycamon
  • Krinocorts
  • NSC 9567
  • Ocriten
  • Ocritena
  • Percorten
  • Percotol
  • Pregn-4-ene-3,20-dione, 21-hydroxy-, acetate
  • Primocort
  • Primocortan
  • Sincortex
  • Syncort
  • Syncorta
  • Syncortyl
  • Unidocan
  • BRN 2570798
  • Corticosterone, deoxy-, acetate
  • Descornaq
  • Desocort
  • Docaquosum
  • Doxatone
  • EINECS 200-275-9
  • Mincortid
  • Organon's Doca Acetate
  • Percortene
  • Cortormon
  • Decorton
  • Desoxykorton
  • UNII-6E0A168OB8

Applications:

Separation of Deoxycorticosterone acetate on Newcrom R1 HPLC column

February 16, 2018
Separation of Deoxycorticosterone acetate on Newcrom C18 HPLC column

Deoxycorticosterone acetate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Deoxycorticosterone acetate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.