2-Hydroxyacetophenone

2-Hydroxyacetophenone structural formula

CAS Number118-93-4
Molecular FormulaC8H8O2
Molecular Weight136.150
InChI KeyJECYUBVRTQDVAT-UHFFFAOYSA-N
LogP1.92
Synonyms
  • 2-Hydroxyacetophenone
  • 1-(2-Hydroxyphenyl)ethan-1-one
  • Ethanone, 1-(2-hydroxyphenyl)-
  • 118-93-4
  • 4-08-00-00320
  • Ethanone, 1-(2-hydroxyphenyl)-
  • 1-(2-Hydroxyphenyl)ethanone
  • 1-(6-Hydroxyphenyl)ethanone
  • 2-ACETYLPHENOL
  • 2'-hidroxiacetofenona
  • 2'-Hydroxyacetophenon
  • 2'-Hydroxyacetophenone
  • 2-Hydroxyphenyl methyl ketone
  • 2-Hydroxyphenylethanone
  • Acetophenone, 2'-hydroxy-
  • ACETOPHENONE, 2-HYDROXY-
  • Acetophenone, o-hydroxy-
  • Methyl 2-hydroxyphenyl ketone
  • NSC 16933
  • NSC 44452
  • NSC 83568
  • NSC 9263
  • o-Acetylphenol
  • O-HYDROXY-ACETOPHENON
  • O-HYDROXYACETOPHENONE
  • o-Hydroxyhypnone
  • o-Hydroxyphenyl methyl ketone
  • BRN 0386123
  • EINECS 204-288-0
  • FEMA No. 3548
  • UNII-3E533Z76W0

Applications:

Separation of 2-Hydroxyacetophenone on Newcrom R1 HPLC column

May 16, 2018
Separation of 2-Hydroxyacetophenone on Newcrom R1 HPLC column

2-Hydroxyacetophenone can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
2-Hydroxyacetophenone
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.