| CAS Number | 110-44-1 |
|---|---|
| Molecular Formula | C6H8O2 |
| Molecular Weight | 112.128 |
| InChI Key | WSWCOQWTEOXDQX-MQQKCMAXSA-N |
| LogP | 1.33 |
| Synonyms |
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Applications:
HPLC Method for Analysis of Potassium Sorbate on Newcrom BH Column
May 10, 2022
Potassium Sorbate is a popular preservative used in a wide variety of foods, wines, and personal-care products. Potassium Sorbate can be retained and analyzed on a mixed-mode Newcrom BH column with a mobile phase consisting of water, Acetonitrile (MeCN), and Sulfuric acid (H2SO4). This analytical method can be UV detected at 210 nm with high resolution and peak symmetry.
Application Column
Newcrom BH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsSorbic acid
HPLC Separation of Levulinic acid and Sorbic Acid on Newcrom BH Column
June 30, 2020
Levulinic acid is used as a precursor for a wide variety of compounds and is used extensively in pharmaceuticals and cosmetics industries. Sorbic acid is used as a preservative in food and drinks. The two acids can be separated in HPLC using Newcrom BH mixed-mode column using a mobile phase of acetonitrile (ACN) and water and either phosphoric acid (H3PO4) or formic acid (FA) as buffer allowing the the use of either UV or MS detector.
| Column | Newcrom BH, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O |
| Buffer | H3PO4, Formic Acid |
| Flow Rate | 1.0 ml/min |
| Detection | UV 210, 266 nm |
| Class of Compounds | Acid |
| Analyzing Compounds | Sorbic Acid , Levulinic Acid |
Application Column
Newcrom BH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsSorbic acid
HPLC Separation of Sorbic, Fumaric, Malonic Acids on Newcrom BH Column
June 25, 2020
Acids with different strengths can be retained and elution order controlled by the use of a mixed-mode column, which has an ion-exchange component in addition to hydrophobic retention. In this example, the Newcrom BH mixed-mode column was used to separate fumaric, malonic and sorbic acids in HPLC. Sorbic acid was mostly retained by hydrophobicity, while fumaric and malonic acids were also retained by the adjustment strength of the mobile phase
| Column | Newcrom BH, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O – 20/80% |
| Buffer | H3PO4 |
| Flow Rate | 1.0 ml/min |
| Detection | UV 200nm |
| Class of Compounds | Acid |
| Analyzing Compounds | Sorbic Acid, Levulinic Acid |
Application Column
Newcrom BH
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select optionsMalonic Acid
Sorbic acid
Separation of Sorbic acid on Newcrom R1 HPLC column
February 16, 2018
Sorbic acid can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options