Scopolamine hydrobromide

Scopolamine hydrobromide structural formula

CAS Number114-49-8
Molecular FormulaC17H22BrNO4
Molecular Weight384.270
InChI KeyWTGQALLALWYDJH-MOUKNHLCSA-N
LogP0.900
Synonyms
  • Scopolamine hydrobromide
  • (1R,2R,4S,5S,7s)-9-Methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]nonan-7-yl (2S)-3-hydroxy-2-phenylpropanoate--hydrogen bromide (1/1)
  • Benzeneacetic acid, alpha-(hydroxymethyl)-, (1R,2R,4S,5S)-9-methyl-3-oxa-9-azatricyclo[3.3.1.0~2,4~]non-7-yl ester, (alphaS)-, hydrobromide (1:1)
  • 114-49-8
  • 1-Hyoscine hydrobromide
  • Scopolamine bromide
  • Hydroscine hydrobromide
  • Hyocine F hydrobromide
  • Hyoscine hydrobromide
  • Hysco
  • Kwells
  • Scopos
  • Sea Legs
  • Sereen
  • Triptone
  • Wellcome Brand Scopolamine hydrobromide Injection
  • Benzeneacetic acid, alpha -(hydroxymethyl)-,(1 alpha,2 beta,4 beta,5 alpha,7 beta)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide (1:1), (alpha S)-
  • Benzeneacetic acid, alpha -(hydroxymethyl)-,(1 alpha,2 beta,4 beta,5 alpha,7 beta)-9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, (alpha S)-
  • Benzeneacetic acid, alpha -(hydroxymethyl)-, 9-methyl-3-oxa-9-azatricyclo[3.3.1.02,4]non-7-yl ester, hydrobromide, [7(s)-(1 alpha,2 beta,4 beta,5 alpha,7 beta)]-
  • Beldavrin
  • EINECS 204-050-6
  • Euscopol
  • Isoscopil
  • NSC 61806
  • Scopamin
  • 1-Scopolamine-hydrobromide
  • Scopolammonium bromide
  • Tranaxine
  • (-)-Hyoscine hydrobromide
  • 1alpha H,5alpha H-Tropan-3-alpha-ol, 5beta,7beta-epoxy-, (-)-tropate (ester), hydrobromide
  • UNII-R3K67DRL3J
  • (-)-hyoscine hydrobromide (anhydrous)
  • (-)-scopolamine bromide
  • (-)-scopolamine bromide (anhydrous)
  • (-)-scopolamine hydrobromide
  • (-)-scopolamine hydrobromide (anhydrous)
  • hyoscine bromide
  • hyoscine bromide (anhydrous)
  • scopolamine bromide (anhydrous)
  • scopolaminium bromide
  • scopolaminium bromide (anhydrous)
  • scopolammonium bromide
  • scopolammonium bromide (anhydrous)
  • scopolamine hydrobromide (anhydrous)
  • 70-50-8
  • 8013-72-7

Applications:

Separation of Scopolamine hydrobromide on Newcrom R1 HPLC column

February 16, 2018
Separation of Scopolamine hydrobromide on Newcrom C18 HPLC column

Scopolamine hydrobromide can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
Scopolamine hydrobromide
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.