HPLC Separation of Sodium, Potassium Ions and Tetramethylammonium Chloride on Newcrom AH Column

HPLC.cloud View on hplc.cloud Tetramethylammonium chloride is a quaternary ammonium salt used widely as a reagent in industrial applications.  It can be separated from sodium and potassium chlorides on a mixed-mode Newcrom AH column with a simple isocratic MS-compatible mobile phase of water, acetonitrile (ACN) and ammonium formate (AmFm) buffer.


Column Newcrom AH, 4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 50/50%
Buffer AmFm pH 3.0- 10 mM
Flow Rate 1.0 ml/min
Detection CAD (Corona) MS- compatible mobile phase


Class of Compounds Hydrophilic, Metal, Ion
Analyzing Compounds Sodium, Potassium, Tetramethylammonium

Application Analytes: