| CAS Number | 98-01-1 |
|---|---|
| Molecular Formula | C5H4O2 |
| Molecular Weight | 96.085 |
| InChI Key | HYBBIBNJHNGZAN-UHFFFAOYSA-N |
| LogP | 0.41 |
| Synonyms |
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Applications:
Substituted Furans Separation on Newcrom R1
February 10, 2021
Furan is a chemical contaminant that forms in some foods during traditional heat treatment techniques, such as cooking, jarring, and canning. The compounds can be retained and separated in HPLC using Newcrom R1 reverse-phase column. The analytical method’s mobile phase consists of a gradient of acetonitrile (ACN) in water with phosphoric acid (H3PO4) buffer and using UV detection at 210 and 275 nm.
| Column | Newcrom R1, 4.6×150 mm, 5 µm, 100A |
| Mobile Phase | MeCN/H2O – 5/95% |
| Buffer | H3PO4 – 0.1% |
| Flow Rate | 1.0 ml/min |
| Detection | 210, 275 nm |
| Class of Compounds | Hydrophilic, Acid, Aldehyde |
| Analyzing Compounds | 3,4-Bis(hydroxymethyl)furan, 5-Hydroxymethyl-2-furaldehyde (5-HMF), 5-(Hydroxymethyl)furan-2-carboxylic Acid, Furfuryl Alcohol, Furfural, 2-furancarboxylic acid |
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options3,4-Bis(hydroxymethyl)furan
5-Hydroxymethyl-2-furaldehyde (5-HMF)
5-Hydroxymethyl-2-furancarboxylic acid
Furfural
Furfuryl alcohol
Separation of Furfural on Newcrom R1 HPLC column
February 16, 2018
Furfural can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
Select options