DMF (Dimethylformamide)

CAS Number68-12-2
Molecular FormulaHCON(CH3)2
Molecular Weight73.09
InChI KeyZMXDDKWLCZADIW-UHFFFAOYSA-N
LogP-1
Synonyms
  • N,N-DIMETHYLFORMAMIDE
  • Dimethylformamide
  • 68-12-2
  • N,N-Dimethylmethanamide
  • Dimethyl formamide
  • N-Formyldimethylamine
  • Formamide, N,N-dimethyl-
  • DMF
  • Dimethylformamid
  • Dimetilformamide
  • Dwumetyloformamid
  • DMFA
  • Formyldimethylamine
  • N,N-Dimethyl formamide
  • Dimethylforamide
  • Dimetylformamidu
  • DMF (amide)
  • NCI-C60913
  • n,n,dimethylformamide
  • N,N-Dimethylformamid
  • Dimethylamid kyseliny mravenci
  • Caswell No. 366A
  • Dimetylformamidu [Czech]
  • Dimethylformamid [German]
  • Dimetilformamide [Italian]
  • Dwumetyloformamid [Polish]
  • dimethyl-Formamide
  • HSDB 78
  • U-4224
  • UNII-8696NH0Y2X
  • CCRIS 1638
  • N,N-Dimetilformamida [Spanish]
  • n,n-dimethyl-Formamide
  • N, N-dimethylformamide

Applications:

HPLC Method For Analysis Of Dimethylformamide and Dimethylacetamide on Primesep 100 Column

April 12, 2022

Separation type: Liquid Chromatography Mixed-mode

 


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High Performance Liquid Chromatography (HPLC) Method for Analysis of Dimethylformamide and Dimethylacetamide

 

Condition
Column Primesep 100, 4.6×150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O – 5/95%
Buffer H3PO4 – 0.2%
Flow Rate 1.0 ml/min
Detection UV, 200 nm,

 

Description
Class of Compounds
 Amide
Analyzing Compounds TDimethylformamide,  Dimethylacetamide

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
DMA (Dimethylacetamide)
DMF (Dimethylformamide)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Separation of Mixture of DMF and DMSO

April 25, 2019

HPLC Method for DMF (Dimethylformamide), DMSO (Dimethyl sulfoxide) on SHARC 1 by SIELC Technologies

High Performance Liquid Chromatography (HPLC) Method for Analysis of DMF (Dimethylformamide), DMSO (Dimethyl sulfoxide).

Dimethylformamide, DMF, is primarily used as an organic solvent and is miscible with water and most other organic liquids. Dimethyl sulfoxide (DMSO) is also a solvent. It can dissolve both polar and nonpolar compounds and is miscible with water and other organic liquids. Both compounds can be retained and separated using anhydrous (water-free) conditions using HPLC by SHARC 1 column, which uses hydrogen-bonding as a separation mechanism. The method uses a gradient of acetonitrile (ACN) and methanol (MeOH) mobile phase without the need for a buffer. UV detection used at 220nm.

Condition
Column SHARC 1, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase Gradient MeCN – 98-85 %, 10 min
Buffer No
Flow Rate 1.0 ml/min
Detection UV, 220 nm

 

Description
Class of Compounds
 Drug, Basic, Hydrophobic, Ionizable, Zwitterionic
Analyzing Compounds DMF (Dimethylformamide), DMSO (Dimethyl sulfoxide)

 

Application Column

SHARC 1

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
DMF (Dimethylformamide)
DMSO (Dimethyl sulfoxide)
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.