Coumarin

Coumarin structural formula

UV Spectra of Coumarin

UV Coumarin spectra UV Coumarin spectra
CAS Number91-64-5
Molecular FormulaC9H6O2
Molecular Weight146.146
InChI KeyZYGHJZDHTFUPRJ-UHFFFAOYSA-N
LogP1.39
Synonyms
  • Coumarin
  • 2H-1-Benzopyran-2-one
  • 91-64-5
  • 2H-1-Benzopyran-2-one
  • Chromen-2-one
  • 5-17-10-00143
  • 1,2-Benzopyrone
  • 2-Propenoic acid, 3-(2-hydroxyphenyl)-, ?-lactone
  • 5,6-Benzo-2-pyrone
  • Benzo-?-pyrone
  • cis-o-Coumarinic acid lactone
  • Coumarine
  • Coumarinic anhydride
  • Cumarin
  • cumarina
  • NSC 8774
  • o-Hydroxycinnamic acid lactone
  • Tonka bean camphor
  • 2H-1-Benzopyran, 2-oxo-
  • 2H-Benzo(b)pyran-2-one
  • Benzo-alpha-pyrone
  • 5,6-Benzo-alpha-pyrone
  • BRN 0383644
  • Caswell No. 259C
  • Cinnamic acid, o-hydroxy-, delta-lactone
  • cis-o-Coumaric acid anhydride
  • o-Coumaric acid lactone
  • Coumarinic lactone
  • EINECS 202-086-7
  • EPA Pesticide Chemical Code 127301
  • 3-(2-Hydroxyphenyl)-2-propenoic delta-lactone
  • NCI C07103
  • 2-Propenoic acid, 3-(2-hydroxyphenyl)-delta-lactone
  • UNII-A4VZ22K1WT
  • 1, 2-Benzopyrone
  • 2-Oxo-1,2-benzopyran
  • 2-Oxo-2H-1-Benzopyran
  • 2-Propenoic acid, 3-(2-hydroxyphenyl)-, delta-lactone
  • 2H-Chromen-2-one
  • 2H-Chromen-2-one (ACD/Name 4.0)
  • 2H-benzo[b]pyran-2-one
  • Benzo-alpha-pyrone
  • Kumarin
  • O-Hydroxycinnamic lactone
  • O-Hydroxyzimtsaure-lacton
  • o-hydroxycinnamic acid delta-lactone
  • {2H-Benzo[b]pyran-2-one}

Applications:

HPLC Method for Analysis of Coumarin

July 18, 2018

HPLC Method for Coumarin on Newcrom R1 by SIELC Technologies

HPLC Method for Analysis of Coumarin

High Performance Liquid Chromatography (HPLC) Method for Analysis of Coumarin 

Coumarin is an aromatic chemical that is used as a fragrance ingredient. It has a sweet earthy scent and is typically found in Tonka beans, cinnamon, woodruff, bison grass, and green tea. Besides a pleasant smell it had anti-inflammatory, antibacterial, and antifungal properties.

Coumarin an be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes an isocratic method with a simple mobile phase consisting of water and acetonitrile (MeCN) with a phosphoric acid buffer. Detection is performed using UV.

ColumnNewcrom R1, 3.2 x 100 mm, 3 µm, 100 A, dual ended
Mobile PhaseMeCN/H2O – 25/75%
BufferH3PO4 – 0.1 %
Flow Rate0.5 ml/min
DetectionUV, 276 nm
Class of Compounds
Drug, Flavouring substance, Hydrophobic, Neutral
Analyzing CompoundsCoumarin

Application Column

Newcrom R1

Column Diameter: 3.2 mm
Column Length: 100 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended

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Application Analytes:
Coumarin
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.