Hydroxybenzoic Acid

Hydroxybenzoic Acid structural formula

CAS Number99-96-7
Molecular FormulaC7H6O3
Molecular Weight138.122
  • 4-Hydroxybenzoic acid
  • Benzoic acid, 4-hydroxy-
  • 99-96-7
  • p-Hydroxybenzoic acid
  • 4-Carboxyphenol
  • Benzoic acid, 4-hydroxy-
  • 4-Hydroxybenzoesaure
  • Acide 4-hydroxybenzoique
  • acido 4-hidroxibenzoico
  • Benzoic acid, p-hydroxy-
  • NSC 4961
  • Paraben-acid
  • p-Carboxyphenol
  • p-Salicylic acid
  • EINECS 202-804-9
  • Acido p-idrossibenzoico
  • Kyselina 4-hydroxybenzoova
  • p-Oxybenzoesaure
  • UNII-JG8Z55Y12H
  • 4-Hydroxy-benzoate
  • 4-Hydroxy-benzoesaeure
  • 4-Hydroxy-benzoic acid
  • 4-Hydroxybenzoate
  • p-Hydroxy-Benzoate
  • p-Hydroxy-Benzoic acid
  • p-Hydroxybenzoate
  • p-Salicylate


HILIC Separation of Carboxylic Acids


Hydrophilic acids are separated on Obelisc N mixed-mode HILIC column. Seven carboxylic acids are separated based on their polarity and pKa values. Changes in ionization states of acids and stationary phase can be used to control elution order of organic and inorganic acids.

Application Column

Obelisc N

SIELC has developed the mixed-mode Obelisc™ columns to be the first commercially available columns with Liquid Separation Cell technology (LiSC™). This cost effective duo can replace multiple HPLC columns such as reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion- exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters  - Buffer concentration, Buffer pH, and Organic Modifier Concentration  - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options
Application Analytes:
Fumaric Acid
Hydroxybenzoic Acid
Malic Acid
Mandelic Acid
Methylmalonic Acid
Organic Acids
Succinic Acid
Tartaric Acid

Application Detection:
ELSD Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.