SIELC Presents: Single-Ended HPLC Column

PVP HPLC Column

SIELC Presents: Single-Ended HPLC Column

SIELC Technologies, a pioneer in chromatography innovation, introduces a single-ended HPLC column — a revolutionary new design that redefines how columns are connected and used in high-performance liquid chromatography. For decades, laboratories have relied on the same standard column format — and have dealt with the same recurring problems: leaky fittings, clogged junctions, dead volume, and the constant hassle of tubing and connection selection.


Key Benefits:

  • No fittings or tubing required eliminates leaks, complex installation, and the need to match tubing length or ID.
  • Zero dead volume thanks to a direct connection via a dedicated adapter.
  • Leak containment in case of pressure failure, solvent remains inside the adapter with no external leakage.
  • Tool-free column replacement — disconnect the column without touching the fittings.
  • Aluminum body — ensures efficient heat transfer and provides a smooth, label-friendly surface even on the shortest columns.
  • Trace-Level Sensitivity – Exceptionally low bleed, suitable for LC-MS and advanced detection methods.

All SIELC and Traditional Columns Available in a New Format
C18, HILIC, Ion Exchange, Mixed-Mode, Ion Exclusion, Protein, BIST, and more.

🔗 Learn more: Information about Single-Ended HPLC Column or Brochure