| CAS Number | 2492423-29-5 |
|---|---|
| Molecular Formula | C13H19N3O7 |
| Molecular Weight | 329.31 |
| InChI Key | HTNPEHXGEKVIHG-QCNRFFRDSA-N |
| LogP | -0.8 |
| Synonyms |
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Applications:
Uv-Vis Spectrum of Molnupiravir
January 12, 2026
If you are looking for optimized HPLC method to analyze Molnupiravir (EIDD-2801, MK-4482) check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.
HPLC Method for Analysis of Molnupiravir on Newcrom R1 Column
June 15, 2022
Separation type: Liquid Chromatography Reverse Phase.
High Performance Liquid Chromatography (HPLC) Method for Analysis of Molnupiravir
Molnupiravir is a popular antiviral drug that in hibits RNA replication in certain viruses. It gained recent notoriety in its ability to help treat COVID-19 infections from the SARS-CoV-2 virus. Molnupiravir can be separated and analyzed on a Newcrom R1 reverse-phase column using a simple gradient analytical method with a mobile phase consisting of just Acetonitrile (MeCN) and water (with no ionic modifier). This analysis method can be UV detected at 235 nm with high resolution and peak symmetry.
| Column | Newcrom R1, 3.2×100 mm, 100A |
| Mobile Phase | MeCN -15% |
| Buffer | No |
| Flow Rate | 0.5 ml/min |
| Detection | UV 235nm |
| Class of Compounds | Drug |
| Analyzing Compounds | Molnupiravir |
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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