Menadiol

Menadiol structural formula

CAS Number481-85-6
Molecular FormulaC11H10O2
Molecular Weight174.200
InChI KeyZJTLZYDQJHKRMQ-UHFFFAOYSA-N
LogP2.15
Synonyms
  • Menadiol
  • 2-Methylnaphthalene-1,4-diol
  • 1,4-Naphthalenediol, 2-methyl-
  • 481-85-6
  • BRN 1638194
  • EINECS 207-573-8
  • 2-Methyl-1,4-naphthohydroquinone
  • Reduced vitamin K3
  • UNII-VQ093653DO
  • 2-Methyl-1,4-naphthoquinol
  • 2-Methylhydronaphthoquinone
  • 2-Methylnaphthalene-1,4-diol
  • Dihydrovitamin K3
  • Methylnaphthohydroquinone
  • Reduced menadione
  • Reduced vitamin K3
  • Vitamin K3H2

Applications:

Separation of Menadiol on Newcrom R1 HPLC column

February 16, 2018
Separation of Menadiol on Newcrom C18 HPLC column

Menadiol can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Menadiol
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.