Isoproturon

Isoproturon structural formula

CAS Number34123-59-6
Molecular FormulaC12H18N2O
Molecular Weight206.290
InChI KeyPUIYMUZLKQOUOZ-UHFFFAOYSA-N
LogP2.87
Synonyms
  • Isoproturon
  • N,N-Dimethyl-N'-[4-(propan-2-yl)phenyl]urea
  • Urea, N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]-
  • 34123-59-6
  • 3-(4-Isopropyl-phenyl)-1,1-dimethyl-urea
  • Urea, N,N-dimethyl-N'-[4-(1-methylethyl)phenyl]-
  • 3-(4-isopropilfenil)-1,1-dimetilurea
  • 3-(4-Isopropylphenyl)-1,1-dimethylharnstoff
  • 3-(4-isopropylphenyl)-1,1-dimethylurea
  • 3-(4-isopropylphenyl)-1,1-dimethyluree
  • Arelon Dyspersyjny
  • Arelon R
  • Graminon
  • Hora-Flo
  • Hytane 500L
  • IPU Stefes
  • Izoturon
  • N'-(4-Isopropylphenyl)-N,N-dimethylurea
  • N-(4-Isopropylphenyl)-N',N'-dimethylurea
  • N'-(p-Cumenyl)-N,N-dimethylurea
  • N'-(p-Isopropylphenyl)-N,N-dimethylurea
  • N,N-Dimethyl-N'-(4-isopropylphenyl)urea
  • N,N-Dimethyl-N'-[4-(1-methylethyl)phenyl]urea
  • Nocilon
  • Protugan
  • Tolkan Flo
  • Urea, 3-p-cumenyl-1,1-dimethyl-
  • Belgran
  • BRN 2214033
  • N,N-Dimethyl-N'-(4-(1-methylethyl)phenyl)urea
  • EINECS 251-835-4
  • Zodiac TX
  • N-(4-Isopropylphenyl)-N',N'-dimethylharnstoff
  • N-(Isopropyl-4-phenyl)-N',N'-dimethyluree
  • UNII-66066K098P
  • 1,1-dimethyl-3-(p-isopropylphenyl)-urea
  • 3-p-cumenyl-1,1-dimethylurea
  • N-4-isopropylphenyl-N,N-dimethylurea

Applications:

Separation of Isoproturon on Newcrom R1 HPLC column

February 16, 2018
Separation of Isoproturon on Newcrom C18 HPLC column

Isoproturon can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Isoproturon
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.

HPLC Method for Analysis of Pesticides: Isoproturon, Diuron, Acenaphthene, Carbendazim

July 11, 2017

Isoproturon is an agricultural herbicide with a tendency to adsorb to soils, which leads to it entering bodies of water. In that water, it is highly toxic for algae and oysters, while long term exposure to the pesticide affects the growth of fish. Diuron is a pre-emergent that is used for non-crop areas as well as with many agricultural crops. It has a low acute toxicity to mammals. It can cause irritation of nose and throat.if inhaled and irritation of eyes if comes in contact with the eyes. Acenaphthene is derived from coal tar and has many used such as dyes, pharmaceuticals, insecticides, fungicides, and plastics. It is harmful if ingested, inhaled or comes in contact with skin, and can cause irritations to skin, eyes, upper respiratory tract, and mucous membranes Carbendazim, also known as mercazole, is a broad-spectrum benzimidazole fungicide. It’s used mostly as a worm control agent in places like tennis courts and golf greens. Sometimes it is also used to control plant diseases in cereals and fruits. Primesep 100, a reverse-phase column, contains embedded acidic ionizable groups and can retain Isoproturon, Diuron, Acenaphthene, and Carbendazim. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

 

Condition

Column Primesep 100, 3.2×100 mm, 5 µm, 100A
Mobile Phase Gradient MeCN – 35-85%, 6 min , 4 min hold
Buffer Gradient H2SO4 – 0.05- 0.15%, 6 min, 4 min hold
Flow Rate 0.6 ml/min
Detection UV, 230 nm

 

Description

Class of Compounds
 Herbicide, Acid, Hydrophilic, Ionizable
Analyzing Compounds Isoproturon, Diuron, Acenaphthene, Carbendazim

 

Application Column

Primesep 100

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

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Application Analytes:
Acenaphthene
Carbendazim
Diuron
Isoproturon
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.