Hydralazine hydrochloride

Hydralazine hydrochloride structural formula

CAS Number304-20-1
Molecular FormulaC8H9ClN4
Molecular Weight196.640
InChI KeyZUXNZUWOTSUBMN-UHFFFAOYSA-N
LogP0.821
Synonyms
  • Hydralazine hydrochloride
  • 1-Hydrazinylphthalazine--hydrogen chloride (1/1)
  • Phthalazine, 1-hydrazinyl-, hydrochloride (1:1)
  • 304-20-1
  • 1-Hydrazinylphthalazine hydrochloride (1:1) (1(2H)-Phthalazinone hydrazone, monohydrochloride)
  • Aiselazine
  • Apresine
  • Apresoline hydrochloride
  • Apresoline-esidrix
  • Dralzine
  • EINECS 206-151-0
  • Hyperazin
  • Hyperex
  • Lopress
  • Nor-press 25
  • NSC 89394
  • 1(2H)-Phthalazinone, hydrazone, hydrochloride
  • Phthalazinone, hydrazone, monohydrochloride
  • Rolazine
  • Slow-Apresolin
  • UNII-FD171B778Y
  • 1(2H)-Phthalazinone hydrazone hydrochloride
  • 1-Hydrazinophthalazine hydrochloride
  • 1-Hydrazinophthalazine monohydrochloride
  • Hydralazine HCl
  • Hydralazine chloride
  • Hydralazine monohydrochloride
  • Phthalazinone hydrazone monohydrochloride
  • 1202866-95-2
  • 40671-54-3

Applications:

Separation of Hydralazine hydrochloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Hydralazine hydrochloride on Newcrom C18 HPLC column

Hydralazine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Hydralazine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.