HPLC method for Phenol – Acetone production and impurities

High Performance Liquid Chromatography (HPLC) Method for Analysis of Phenol, 2-Phenyl-propanol, Acetophenone, Cumene Hydroperoxide, Cumene, Dicumyl Peroxide

Phenol is an organic compound with the molecular formula C6H5OH.

Properties: Appearance: Typically white crystals that turn a light pink due to oxidation.

Molecular weight: ~94.11 g/mol

Solubility: Soluble in water and alcohol.

Uses: Topical skin disinfectant.  

2-Phenyl-propanol is an organic compound with the molecular formula C9H12O.

Properties: Appearance: Typically a white or yellow odorless solid.

Molecular weight: ~136.19 g/mol

Solubility: Soluble in organic solvents.

Uses: Organic synthesis.  

Acetophenone is an aromatic ketone with the molecular formula C6H5COCH3.

Properties: Appearance: Typically a colorless or yellow liquid with a pungent odor.

Molecular weight: ~120.4 g/mol

Solubility: Soluble in organic solvents.

Uses: Fragrance ingredient.  

Cumene Hydroperoxide is an organic compound with the molecular formula C9H12O2.

Properties: Appearance: Typically a colorless or yellow liquid with a pungent odor.

Molecular weight: ~152.19 g/mol

Solubility: Soluble in organic solvents.

Uses: Used in production of phenol and acetone.    

Cumene is a hydrocarbon with the molecular formula C9H12.

Properties: Appearance: Typically a colorless liquid with a pungent odor.

Molecular weight: ~120.19 g/mol

Solubility: Soluble in organic solvents.

Uses: Used in production of phenol and acetone.  

Dicumyl Peroxide is a organic peroxide with the molecular formula C18H22O2.

Properties: Appearance: Typically white crystals.

Molecular weight: ~270.37 g/mol

Solubility: Soluble in organic solvents.

Uses: Used in production of rubber and plastics.   Phenol, 2-Phenyl-propanol, Acetophenone, Cumene Hydroperoxide, Cumene, and Dicumyl Peroxide can be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes an gradient method with a simple mobile phase consisting of water, acetonitrile (MeCN). Detection is performed using UV.

Phenol, 2-Phenyl-propanol, Acetophenone, Cumene Hydroperoxide, Cumene, Dicumyl Peroxide can be retained and analyzed using the Newcrom R1 stationary phase column. The analysis utilizes a gradient method with a simple mobile phase consisting of water, acetonitrile (MeCN). Detection is performed using UV.