Folinic acid calcium salt

Folinic acid calcium salt structural formula

CAS Number1492-18-8
Molecular FormulaC20H21CaN7O7
Molecular Weight511.508
InChI KeyKVUAALJSMIVURS-ZEDZUCNESA-L
LogP-2.03
Synonyms
  • Folinic acid calcium salt
  • Calcium (2S)-2-(4-{[(2-amino-5-formyl-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]amino}benzamido)pentanedioate
  • L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1)
  • 1492-18-8
  • L-Glutamic acid, N-[4-[[(2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1)
  • Glutamic acid, N-[p-[[(2-amino-5-formyl-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]amino]benzoyl]-, calcium salt (1:1), L-
  • Calcium 5-formyltetrahydrofolate
  • Calcium folinate
  • Calcium L-folinate
  • Calcium leucovorin
  • Folidan
  • Lederfoline
  • Leucovorin calcium
  • Leucovorin calcium salt
  • NSC 3590
  • Rescuvolin
  • Wellcovorin
  • Calcium citrovorum factor
  • EINECS 216-082-8
  • (+)-L-Folinic acid, calcium salt
  • Folinic acid-SF, calcium salt
  • Leucovorin calcium preservative free
  • Calcii folinas
  • Folinate de calcium
  • Folinato calcico
  • UNII-RPR1R4C0P4
  • 1236362-90-5
  • 6035-86-5
  • 6209-45-6
  • 30771-29-0

Applications:

Separation of Folinic acid calcium salt on Newcrom R1 HPLC column

May 16, 2018
Separation of Folinic acid calcium salt on Newcrom R1 HPLC column

Folinic acid calcium salt can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Folinic acid calcium salt
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.