Fluoroacetic acid

CAS Number9074-77-5
Molecular FormulaC2H3FO2 or CH2FCOOH
Molecular Weight78.04
InChI KeyQEWYKACRFQMRMB-UHFFFAOYSA-N
LogP0.2
Synonyms
  • FLUOROACETIC ACID
  • 2-Fluoroacetic acid
  • 144-49-0
  • Gifblaar poison
  • Cymonic acid
  • Monofluoroacetic acid
  • Monofluoressigsaure
  • Fluoroethanoic acid
  • Acetic acid, 2-fluoro-
  • Acetic acid, fluoro-
  • Acide-monofluoracetique
  • Monofluorazijnzuur
  • Acido monofluoroacetio
  • UNII-AP1JV9U41M
  • HFA
  • Monofluoroacetate
  • UN 2642
  • AP1JV9U41M
  • CHEBI:30775
  • FLUORACETIC ACID
  • Caswell No. 462
  • Monofluorazijnzuur [Dutch]
  • Monofluoressigsaure [German]
  • Acido monofluoracetio
  • Acido monofluoracetio [Italian]
  • Acide-monofluoracetique [French]
  • Acido monofluoroacetio [Italian]
  • HSDB 2082
  • EINECS 205-631-7
  • UN2642
  • EPA Pesticide Chemical Code 075001
  • BRN 1739053
  • AI3-28547
  • fluoro-acetic acid

Applications:

UV-Vis Absorption Spectrum of Fluoroacetic acid

December 18, 2025
Access the UV-Vis Spectrum SIELC Library
UV-Vis Spectrum of Fluoroacetic acid.

If you are looking for optimized HPLC method to analyze Fluoroacetic acid check our HPLC Applications library

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.

 

Application Analytes:
Fluoroacetic acid
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

HPLC Method for Analysis of Fluoroacetic acid, Difluoroacetic acid and Trifluoroacetic acid on BIST A+ Column

July 7, 2022

 

Separation type: Bridge Ion Separation Technology, or BIST™
 

HPLC Method for Analysis of Fluoroacetic acid, Difluoroacetic acid and Trifluoroacetic acid on BIST A+ Column
High Performance Liquid Chromatography (HPLC) Method for Analysis of  Fluoroacetic acid, Difluoroacetic acid and Trifluoroacetic acid

Condition
Column BIST A+, 2.1×100 mm, 3 µm, 100A
Mobile Phase MeCN – 90%
Buffer TMDAP ( N,N,N’,N’-Tetramethyl-1,3-diaminopropane) formate – 5 mM pH 4.0
Flow Rate 0.4 ml/min
Detection Conductivity

 

Description
Class of Compounds
 Acids
Analyzing Compounds Fluoroacetic acid, Difluoroacetic acid and Trifluoroacetic acid

Application Column

BIST A+

BIST™ columns offer a unique and effective way to achieve separations that were traditionally challenging or even impossible with other HPLC columns. With the use of a special mobile phase, these ion exchange columns provide very strong retention for analytes with the same charge polarity as the stationary phase, unlocking new chromatography applications. What makes BIST™ columns stand out is their proprietary surface chemistry, which results in superior selectivity, resolution, and sensitivity. These columns offer a simple, efficient solution for a variety of analytical challenges, making them an excellent choice for researchers and analysts across many different fields. To learn more about the technology that powers BIST™ columns and to explore related applications, check out https://BIST.LC.

Select options
Application Analytes:
Difluoroacetic acid
Fluoroacetic acid
TFA (Trifluoroacetic Acid)
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.