1-Methylnicotinamide

1-Methylnicotinamide

CAS Number3106-60-3
Molecular FormulaC7H9N2O
Molecular Weight137.161
InChI KeyLDHMAVIPBRSVRG-UHFFFAOYSA-O
LogP-2.06
Synonyms
  • N(1)-Methylnicotinamide
  • 3-Carbamoyl-1-methylpyridin-1-ium
  • Pyridinium, 3-(aminocarbonyl)-1-methyl-
  • 3106-60-3
  • 5-22-02-00145
  • 3-(Aminocarbonyl)-1-methylpyridinium
  • BRN 3540351
  • 1-Methyl nicotinamide
  • N(sup 1)-Methylnicotinamide
  • UNII-UM47085BXC
  • 1-Methyl-3-carbamoylpyridinium
  • 1-Methyl-3-carbamoylpyridinium cation
  • 1-methyl-3-pyridin-1-iumcarboxamide
  • 1-methylnicotinamide
  • 1-methylnicotinamide cation
  • 1-methylpyridin-1-ium-3-carboxamide
  • 3-(Aminocarbonyl)-1-methylpyridinium
  • 3-Amido-N-methylpyridinium: 1-methyl-3-Pyridinecarboxamide
  • 3-Carbamoyl-1-methyl-Pyridinium
  • 3-carbamoyl-1-methylpyridin-1-ium
  • I-Methyl nicotinamide
  • N'-Methylnicotinamide
  • N'Methylnicotinamide
  • N-1-Methylnicotinamide
  • N-Methyl-3-carbamidopyridinium
  • N-Methyl-3-carbamoylpyridinium ion
  • N1-Methylnicotinamide
  • Trigonellinamide

Applications:

UV-Vis Spectrum of 1-Methylnicotinamide

July 25, 2024
UV-Vis Spectrum of 1-Methylnicotinamide. Absorption Maxima: 210 nm, 264 nm.

For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. The spectra presented here are measured with an acidic mobile phase that has a pH of 3 or lower.

Application Analytes:
1-Methylnicotinamide
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of Nicotinamide and Related Substances

May 11, 2015

A complex mixture of nicotinamide and related impurities was separated on Obelisc R mixed-mode column. Nicotinamide, methylnicotinamide, nicotinamide adenine mononucleotide, nicotinamide adenine dinucleotide, and adenosine monophosphate were baseline resolved in a 15 minute long method. This mixed-mode approach can be used for analysis of other nucleotides. Obelisc R trimodal column separates this complex mixture based on reversed-phase, cation-exchange and anion-exchange mechanisms. Retention is controlled by amount of ACN, buffer concentration and buffer pH. Additional selectivity can be gained by exploring various buffers within the same pH

Application Column

Obelisc R

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options
Application Analytes:
1-Methylnicotinamide
Adenosine Monophosphate
Nicotinamide
Nicotinamide Adenine Dinucleotide (NAD)
Nicotinamide Adenine Mononucleotide
Application Detection:
ELSD Detection
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.