| CAS Number | 252186-80-4 |
|---|---|
| Molecular Formula | C14H6Cl4O3 |
| Molecular Weight | 364.0 |
| InChI Key | PQQZYNVQDUZLTQ-UHFFFAOYSA-N |
| LogP | 5.7 |
| Synonyms |
|
Applications:
Uv-Vis Spectrum of 2,3-Dichlorobenzoic Anhydride
March 27, 2026
Access the UV-Vis Spectrum SIELC Library
If you are looking for optimized HPLC method to analyze 2,3-Dichlorobenzoic anhydride check our HPLC Applications library
For optimal results in HPLC analysis, it is recommended to measure absorbance at a wavelength that matches the absorption maximum of the compound(s) being analyzed. The UV spectrum shown can assist in selecting an appropriate wavelength for your analysis. Please note that certain mobile phases and buffers may block wavelengths below 230 nm, rendering absorbance measurement at these wavelengths ineffective. If detection below 230 nm is required, it is recommended to use acetonitrile and water as low UV-transparent mobile phases, with phosphoric acid and its salts, sulfuric acid, and TFA as buffers.
For some compounds, the UV-Vis Spectrum is affected by the pH of the mobile phase. This analysis was done with the mobile phase made of 20% acetonitrile and 80% water.
HPLC Method For Analysis Of 2,3-Dichlorobenzoic Anhydride on Primesep S2 Column
February 4, 2022
Separation type: Liquid Chromatography HILIC
High Performance Liquid Chromatography (HPLC) Method for Analysis of 2,3-Dichlorobenzoic anhydride
2,3-Dichlorobenzoic Anhydride is an impurity formed during the production of Lamotrigine, anticonvulsant used to treat epileptic seizures and Bipolar Disorder. Removing 2,3-Dichlorobenzoic Anhydride is paramount for maximizing Lamotrigine purity. 2,3-Dichlorobenzoic Anhydride can be retained and analyzed on a mixed-mode Primesep S2 column with a mobile phase consisting of just Acetonitrile (MeCN) without water or a buffer. This analytical method can be UV detected at 210 nm with high resolution and peak symmetry.
| Column | Primesep S2, 4.6×250 mm, 5 µm, 100A |
| Mobile Phase | MeCN- 100% |
| Buffer | No |
| Flow Rate | 1.0 ml/min |
| Detection | UV 210 nm |
| Class of Compounds | Anhydride |
| Analyzing Compounds | 2,3-Dichlorobenzoic anhydride |
Application Column
Primesep S2
The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.
Select options
