1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-

1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- structural formula

CAS Number605-65-2
Molecular FormulaC12H12ClNO2S
Molecular Weight269.740
InChI KeyXPDXVDYUQZHFPV-UHFFFAOYSA-N
LogP3.11
Synonyms
  • 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-
  • 5-(Dimethylamino)naphthalene-1-sulfonyl chloride
  • 605-65-2
  • 4-14-00-02801
  • 1-(Dimethylamino)-5-naphthalenesulfonyl chloride
  • 5-(Dimethylamino)-1-naphthalenesulfonyl chloride
  • 5-(N,N-Dimethylamino)-1-naphthalenesulfonyl chloride
  • 5-dimethylaminonaphthalene-1-sulphonyl chloride
  • 5-Dimethylaminonaphthalin-1-sulfonylchlorid
  • Chlorure de 5-dimethylaminonaphtalene-1-sulfonyle
  • cloruro de 5-dimetilaminonaftaleno-1-sulfonilo
  • DANSYL CHLORIDE
  • DNS chloride
  • NSC 83616
  • BRN 2217205
  • 1-Chlorosulfonyl-5-dimethylaminonaphthalene
  • Dimethylaminonaphthalenesulfonyl chloride
  • 5-Dimethylaminonaphthalene-1-sulfonyl chloride
  • 5-Dimethylaminonaphthyl-5-sulfonyl chloride
  • EINECS 210-092-6
  • UNII-QMU9166TJ4
  • 1-dimethylaminonaphthalene-5-sulfonyl chloride
  • DNS chloride
  • 558479-38-2

Applications:

Separation of 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- on Newcrom R1 HPLC column

February 16, 2018
Separation of 1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- on Newcrom C18 HPLC column

1-Naphthalenesulfonyl chloride, 5-(dimethylamino)- can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
1-Naphthalenesulfonyl chloride, 5-(dimethylamino)-
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.