Salsalate

Salsalate structural formula

CAS Number552-94-3
Molecular FormulaC14H10O5
Molecular Weight258.230
InChI KeyWVYADZUPLLSGPU-UHFFFAOYSA-N
LogP2.93
Synonyms
  • Salsalate
  • 2-[(2-Hydroxybenzoyl)oxy]benzoic acid
  • Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester
  • 552-94-3
  • Benzoic acid, 2-hydroxy-, 2-carboxyphenyl ester
  • 2-Hydroxybenzoic acid 2-carboxyphenyl ester
  • BENZOATE, 2-HYDROXY-, 2-CARBOXYPHENYL
  • Diacesal
  • Diplosal
  • Disalcid
  • Disalgesic
  • Disalicylic acid
  • Disalyl
  • Mono-Gesic
  • Nobacid
  • NSC 49171
  • o-Salicylsalicylic acid
  • Salflex
  • Salical
  • Salicyl salicylate
  • Salicylic acid, bimol. ester
  • Salicylic acid, salicylate
  • Salicylosalicylic acid
  • Salicyloxysalicylic acid
  • Salicyloylsalicylic acid
  • Salicylsalicylic acid
  • Salsalat
  • salsalato
  • Salysal
  • Sasapirin
  • Sasapyrine
  • Sasapyrinum
  • BRN 2590908
  • EINECS 209-027-4
  • NSC-49171
  • Sal Ester Sal
  • Salicylic acid, bimolecular ester
  • Saloxium
  • Salsalatum
  • UNII-V9MO595C9I
  • 2-Carboxyphenyl salicylate
  • Disalicylsaeure
  • O-Salicylcylsalicylsaeure
  • Salicylic acid bimolecular ester
  • Sasapyrin
  • Sasapyrinum

Applications:

Separation of Salsalate on Newcrom R1 HPLC column

February 16, 2018
Separation of Salsalate on Newcrom C18 HPLC column

Salsalate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Salsalate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.