(-)-Morphine hydrochloride

(-)-Morphine hydrochloride structural formula

CAS Number52-26-6
Molecular FormulaC17H20ClNO3
Molecular Weight321.800
InChI KeyXCKKIKBIPZJUET-VYKNHSEDSA-N
LogP0.721
Synonyms
  • (-)-Morphine hydrochloride
  • (5alpha,6alpha)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol--hydrogen chloride (1/1)
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, (5alpha,6alpha)-, hydrochloride (1:1)
  • 52-26-6
  • (5alpha,6alpha)-17-Methyl-7,8-didehydro-4,5-epoxymorphinan-3,6-diol hydrochloride (1:1)
  • Morphine chlorhydrate
  • Thebametten
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5?,6?)-, hydrochloride
  • 7,8-Didehydro-4,5-epoxy-1,7-methyl-(5?,6?)morphinan-3,6-diol hydrochloride
  • Epimore
  • morfina, clorhidrato
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl- (5?,6?)-, hydrochloride (1:1)
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-(5?,6?)-, hydrochloride
  • Morphinan-3,6-diol, 7,8-didehydro-4,5-epoxy-17-methyl-, hydrochloride, (5?,6?)-
  • Morphinan-3,6?-diol, 7,8-didehydro-4,5?-epoxy-17-methyl-, hydrochloride
  • morphine hydrochloride
  • Morphine monohydrochloride
  • morphine, chlorhydrate
  • Morphinhydrochlorid
  • Theba-Intran
  • EINECS 200-136-2
  • Morphinan-3,6-alpha-diol, 7,8-didehydro-4,5-alpha-epoxy-17-methyl-, hydrochloride
  • Morphine HCl
  • UNII-J28GE0ROVX
  • Morphine chloride
  • morphine-HCl

Applications:

Separation of (-)-Morphine hydrochloride on Newcrom R1 HPLC column

May 16, 2018
Separation of (-)-Morphine hydrochloride on Newcrom R1 HPLC column

(-)-Morphine hydrochloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
(-)-Morphine hydrochloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.