HPLC Determination of Sodium Dodecyl Sulfate on Newcrom BH and Newcrom B Columns

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        Sodium dodecyl sulfate, or sodium lauryl sulfate, is a surfactant used in cleaning and hygienic products. It has a twelve carbon hydrophobic tail attached to a polar sulfate. Dodecyl sulfate can be retained on Newcrom B and BH  columns in under 10 minutes with an MS-compatible mobile phase.


Column Newcrom BH, Newcrom B  4.6x150 mm, 5 µm, 100A
Mobile Phase MeCN/H2O - 70/30%
Buffer AmFm pH 3.0 - 60 mM
Flow Rate 1.0 ml/min
Detection CAD (Corona) MS- compatible mobile phase


Class of Compounds Hydrophobic, Base, Ionizable, Anionic surfactant
Analyzing Compounds Sodium Dodecyl Sulfate
Application Analytes:
Sodium dodecyl sulfate