Glycyrrhizin

Glycyrrhizin structural formula

CAS Number1405-86-3
Molecular FormulaC42H62O16
Molecular Weight822.943
InChI KeyLPLVUJXQOOQHMX-QWBHMCJMSA-N
LogP2.80
Synonyms
  • Glycyrrhizin
  • (3beta)-30-Hydroxy-11,30-dioxoolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
  • Olean-12-en-30-oic acid, 3-[(2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranuronosyl)oxy]-11-oxo-, (3beta)-
  • 1405-86-3
  • 4-18-00-05156
  • ?-D-Glucopyranosiduronic acid, (3?,20?)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-?-D-glucopyranuronosyl-
  • 18?-Glycyrrhizic acid
  • Acide glycyrrhizique
  • acido glicirricico
  • Glycyron
  • Glycyrrhetinic acid glycoside
  • glycyrrhizic acid
  • Glycyrrhizinic acid
  • Glycyrrhizinsaure
  • NSC 167409
  • NSC 234419
  • Potenlini
  • ?-Glycyrrhizin
  • BRN 0077922
  • EINECS 215-785-7
  • alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuron osyl-
  • 18-beta-Glycyrrhizic acid
  • Glycyrrizin
  • UNII-6FO62043WK
  • (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
  • beta-Glycyrrhizin
  • 18beta-Glycyrrhizic acid
  • Neo-Umor
  • (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl-2-O-beta-D-glucopyranuronosyl-alpha-D-glucopyranosiduronic acid
  • alpha-D-Glucopyranosiduronic acid, (3beta,20beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-
  • glyzyrrhizin
  • 1208112-19-9
  • 139014-59-8
  • 18933-02-3
  • 31261-47-9
  • 47897-45-0
  • 47897-48-3
  • 70055-50-4
  • 79165-07-4
  • 947339-02-8

Applications:

Separation of Glycyrrhizin on Newcrom R1 HPLC column

May 16, 2018
Separation of Glycyrrhizin on Newcrom R1 HPLC column

Glycyrrhizin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Glycyrrhizin
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.