Fumaryl chloride

Fumaryl chloride structural formula

CAS Number627-63-4
Molecular FormulaC4H2Cl2O2
Molecular Weight152.961
InChI KeyZLYYJUJDFKGVKB-OWOJBTEDSA-N
LogP0.935
Synonyms
  • Fumaryl chloride
  • (2E)-But-2-enedioyl dichloride
  • 2-Butenedioyl dichloride, (2E)-
  • 627-63-4
  • 4-02-00-02217
  • BRN 1721342
  • EINECS 211-005-4
  • Fumaroyl dichloride
  • Chlorure de fumaryle
  • Dichlorid kyseliny fumarove
  • Fumarylchlorid
  • UNII-B95L4812RG

Applications:

Separation of Fumaryl chloride on Newcrom R1 HPLC column

February 16, 2018
Separation of Fumaryl chloride on Newcrom C18 HPLC column

Fumaryl chloride can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Fumaryl chloride
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.