| CAS Number | 91-53-2 |
|---|---|
| Molecular Formula | C14H19NO |
| Molecular Weight | 217.312 |
| InChI Key | DECIPOUIJURFOJ-UHFFFAOYSA-N |
| LogP | 3.61 |
| Synonyms |
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Applications:
HPLC Method For Analysis Of Ethoxyquin on Newcrom R1 Column
August 23, 2021
HPLC Method for Ethoxyquin on Newcrom R1 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Ethoxyquin
Ethoxyquin is an antioxidant. It was developed in the 1950s as a preservative to control the breakdown of fats in dry pet food or the formation of peroxide in canned pet foods. Ethoxyquin is also used as an insecticide, herbicide, fungicide, post-harvest dip to prevent scald on apples and pears, plant growth regulator, and anti-degradation agent for rubber.
Ethoxyquin can be retained in HPLC on Newcrom R1 reverse-phase column using an isocratic analytical method with a simple mobile phase of water, acetonitrile (MeCN, ACN), and Ammonium Formate (AmFm) buffer. Detection can be achieved with mass spectrometry (MS), evaporative light scattering detection (ELSD), charged aerosol detection (CAD) and UV detected at 275 nm.
| Column | Newcrom R1, 2.1 x 150 mm, 3 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 70/30% |
| Buffer | AmFm pH 3.0 – 10 mM |
| Flow Rate | 0.2 ml/min |
| Detection | UV, 275 nm |
| Class of Compounds |
Antioxidant, insecticide, herbicide, fungicide |
| Analyzing Compounds | Ethoxyquin |
Application Column
Newcrom R1
Column Diameter: 2.1 mm
Column Length: 150 mm
Particle Size: 3 µm
Pore Size: 100 A
Column options: dual ended
HPLC Method For Analysis Of Ethoxyquin on Primesep 200 Column
August 23, 2021
HPLC Method for Ethoxyquin on Primesep 200 by SIELC Technologies
High Performance Liquid Chromatography (HPLC) Method for Analysis of Ethoxyquin
Ethoxyquin is an antioxidant. It was developed in the 1950s as a preservative to control the breakdown of fats in dry pet food or the formation of peroxide in canned pet foods. Ethoxyquin is also used as an insecticide, herbicide, fungicide, post-harvest dip to prevent scald on apples and pears, plant growth regulator, and anti-degradation agent for rubber.
Ethoxyquin can be retained on the Primesep 200 mixed-mode column using an isocratic analytical method with a simple mobile phase of water, acetonitrile (MeCN, ACN), and Ammonium Formate (AmFm) buffer. Detection can be achieved with mass spectrometry (MS), evaporative light scattering detection (ELSD), charged aerosol detection (CAD) and UV detected at 260 nm.
| Column | Primesep 200, 4.6 x 150 mm, 5 µm, 100 A, dual ended |
| Mobile Phase | MeCN/H2O – 50/50% |
| Buffer | AmFm pH 3.0 – 50 mM |
| Flow Rate | 1.0 ml/min |
| Detection | UV, 260 nm |
| Class of Compounds |
Antioxidant, insecticide, herbicide, fungicide |
| Analyzing Compounds | Ethoxyquin |
Application Column
Primesep 200
Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended
Separation of Ethoxyquin on Newcrom R1 HPLC column
May 16, 2018
Ethoxyquin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.
Application Column
Newcrom R1
The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.
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