Dexamethazone metasulfobenzoate sodium

Dexamethazone metasulfobenzoate sodium structural formula

CAS Number3936-02-5
Molecular FormulaC29H32FNaO9S
Molecular Weight598.610
InChI KeyRPBJOYICBFNIMN-RDWMNNCQSA-M
LogP1.57
Synonyms
  • Dexamethazone metasulfobenzoate sodium
  • Sodium 3-({[(11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl]oxy}carbonyl)benzene-1-sulfonate
  • Benzoic acid, 3-sulfo-, 1-[(11beta,16alpha)-9-fluoro-11,17-dihydroxy-16-methyl-3,20-dioxopregna-1,4-dien-21-yl] ester, sodium salt (1:1)
  • 3936-02-5
  • EINECS 223-514-9
  • Sisotek
  • Dexamethason 21-(3-sulfobenzoat)natrium
  • UNII-4T1RAI19H8
  • Dexamethasone metasulfobenzoate sodium
  • Dexamethasone sodium-m-sulfobenzoate
  • Dexamethasone-21-sulphobenzoate sodium
  • Dexapos
  • Santeson
  • dexamethasone sodium m-sulfobenzoate

Applications:

Separation of Dexamethazone metasulfobenzoate sodium on Newcrom R1 HPLC column

February 16, 2018
Separation of Dexamethazone metasulfobenzoate sodium on Newcrom C18 HPLC column

Dexamethazone metasulfobenzoate sodium can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Dexamethazone metasulfobenzoate sodium
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.