Desmopressin

Desmopressin structural formula

CAS Number16679-58-6
Molecular FormulaC46H64N14O12S2
Molecular Weight1069.220
InChI KeyNFLWUMRGJYTJIN-NXBWRCJVSA-N
LogP-3.38
Synonyms
  • Desmopressin
  • 1-{(4R,7S,10S,13S,16S)-7-(2-Amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-13-benzyl-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosane-4-carbonyl}-L-prolyl-L-arginylglycinamide
  • Glycinamide, 1-[[(4R,7S,10S,13S,16S)-7-(2-amino-2-oxoethyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-13-(phenylmethyl)-1,2-dithia-5,8,11,14,17-pentaazacycloeicos-4-yl]carbonyl]-L-prolyl-L-arginyl-
  • 16679-58-6
  • Vasopressin, 1-(3-mercaptopropanoic acid)-8-D-arginine-
  • (1-Deamino-8-D-Arg)-vasopressin
  • [1-?-Mercaptopropionic acid-8-D-arginine]vasopressin
  • [Deamino1-D-arginine8]vasopressin
  • [Desamino-Cys1,D-Arg8]vasopressin
  • 1-(3-Mercaptopropionic acid)-8-D-arginine-vasopressin
  • 1-Deamino-[8-D-arginine]vasopressin
  • 1-Deamino-1-[D-Arg8]-vasopressin
  • 1-Desamino-8-D-arginine-vasopressin
  • 1-Desaminocystine-8-D-arginine-vasopressin
  • 8-D-Arginine deaminovasopressin
  • Adiuretin
  • Adiuretin SD
  • DAV Ritter
  • desmopresina
  • desmopressine
  • Desmospray
  • Glycinamide, N-(3-mercapto-1-oxopropyl)-L-tyrosyl-L-phenylalanyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-D-arginyl-, cyclic (1?5)-disulfide
  • Minirin
  • Peptide, (Xaa-Tyr-Phe-Gln-Asn-Cys-Pro-Arg-Gly), ?
  • Vasopressin, 1-(3-mercaptopropionic acid)-8-D-arginine-
  • Deamino-8-D-arginine, l-, vasopressin
  • 1-Deamino-8-D-arginine vasopressin
  • 1-Desamino-8-D-arginine vasopressin
  • Desamino-8-D-arginine vasopressin, l-
  • EINECS 240-726-7
  • Desmopressinum
  • UNII-ENR1LLB0FP
  • Deamino Arginine Vasopressin

Applications:

Separation of Desmopressin on Newcrom R1 HPLC column

February 16, 2018
Separation of Desmopressin on Newcrom C18 HPLC column

Desmopressin can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Desmopressin
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.