Zemuron

Zemuron structural formula

CAS Number119302-91-9
Molecular FormulaC32H53BrN2O4
Molecular Weight609.691
InChI KeyOYTJKRAYGYRUJK-FMCCZJBLSA-M
LogP1.86
Synonyms
  • Rocuronium bromide
  • (2beta,3alpha,5alpha,16beta,17beta)-17-(Acetyloxy)-3-hydroxy-2-(morpholin-4-yl)-16-[1-(prop-2-en-1-yl)pyrrolidin-1-ium-1-yl]androstane bromide
  • Androstane-3,17-diol, 2-(4-morpholinyl)-16-[1-(2-propen-1-yl)-1-pyrrolidiniumyl]-, bromide, 17-acetate, (2beta,3alpha,5alpha,16beta,17beta)- (1:1)
  • 119302-91-9
  • Pyrrolidinium, 1-[(2β,3α,5α,16β,17β)-17-(acetyloxy)-3-hydroxy-2-(4-morpholinyl)androstan-16-yl]-1-(2-propenyl)-, bromide
  • UNII-I65MW4OFHZ
  • 1-Allyl-1-(3alpha,17beta-dihydroxy-2beta-morpholino-5alpha-androstan-16beta-yl)pyrrolidinium bromide, 17-acetate
  • 17beta-acetoxy-16beta-(1-allylpyrrolidinium-1-yl)-3alpha-hydroxy-2beta-(morpholin-4-yl)-5alphaandrostane

Applications:

Separation Study of Zemuron Active Ingredient in Mixed-Mode HPLC

2010-05-05


Zemuron is an amino steroid used as a muscle relaxant during anesthesia. Zemuron was analyzed by mixed-mode chromatography on a Primesep C HPLC column. Compound is hydrophobic and basic in nature, and retention time on cation-exchange mixed-mode column is controlled by the amount of acetonitrile, buffer concentration and buffer pH. In order to observe cation-exchange interaction on a Primesep C column, mobile phase pH should be maintained between 3-7.

Application Column

Primesep C

The Primesep family of mixed-mode columns offer a wide variety of stationary phases with an unprecedented selectivity in the separation of a broad array of chemical compounds and in multiple applications. Corresponding Primesep guard columns are available with all stationary phases and do not require holders. SIELC offers a method development service which is available for all customers. Ask about our special custom LC-phases tailored for specific separations.

Select options
Application Analytes:
Zemuron
Application Detection:
ELSD Detection
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.