Butanedioic acid, methylene-, diethyl ester

Butanedioic acid, methylene-, diethyl ester structural formula

CAS Number2409-52-1
Molecular FormulaC9H14O4
Molecular Weight186.208
InChI KeyZEFVHSWKYCYFFL-UHFFFAOYSA-N
LogP1.86
Synonyms
  • Butanedioic acid, methylene-, diethyl ester
  • Diethyl 2-methylidenebutanedioate
  • Butanedioic acid, 2-methylene-, diethyl ester
  • 2409-52-1
  • Diethyl itaconate
  • Ethyl itaconate
  • Itaconic acid diethyl ester
  • NSC 1794
  • NSC 67389
  • Succinic acid, methylene-, diethyl ester

Applications:

Separation of Butanedioic acid, methylene-, diethyl ester on Newcrom R1 HPLC column

February 16, 2018
Separation of Butanedioic acid, methylene-, diethyl ester on Newcrom C18 HPLC column

Butanedioic acid, methylene-, diethyl ester can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Butanedioic acid, methylene-, diethyl ester
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us by e-mail: support@sielc.com or by phone: 847-229-2629.