Betaine

Betaine

CAS Number107-43-7
Molecular FormulaC5H11NO2
Molecular Weight117.148
InChI KeyKWIUHFFTVRNATP-UHFFFAOYSA-N
LogP-2.72
Synonyms
  • Betaine
  • (Trimethylazaniumyl)acetate
  • Methanaminium, 1-carboxy-N,N,N-trimethyl-, inner salt
  • 107-43-7
  • 4-04-00-02369
  • Methanaminium, 1-carboxy-N,N,N-trimethyl-, inner salt
  • (Carboxymethyl)trimethylammonium hydroxide inner salt
  • (Trimethylammonio)acetate
  • 2-(Trimethylammonio)ethanoic acid, hydroxide, inner salt
  • Abromine
  • Aminocoat
  • Ammonium compounds, substituted, (carboxymethyl)trimethyl-, hydroxide, inner salt
  • Aquadew AN 100
  • Betafin
  • Betafin BCR
  • Betafin BP
  • Betafin BP 20
  • betaina
  • Cystadane
  • Fencaijian
  • FinnStim
  • Glycine betaine
  • Glycine, trimethylbetaine
  • Glycocoll betaine
  • Glycylbetaine
  • Greenstim
  • Loramine AMB 13
  • Methanaminium, 1-carboxy-N,N,N-trimethyl-, hydroxide, inner salt
  • N,N,N-Trimethylglycine
  • Oxyneurine
  • Rubrine C
  • Trimethylbetaine
  • Trimethylglycine
  • Trimethylglycocoll
  • α-Earleine
  • BRN 3537113
  • (Carboxymethyl)trimethylammonium hydroxide, inner salt
  • EINECS 203-490-6
  • Jortaine
  • NSC 166511
  • Glykokollbetain
  • UNII-3SCV180C9W
  • Acidin-Pepsin
  • Novobetaine
  • Hepastyl
  • (trimethylammoniumyl)acetate
  • 1-Carboxy-N,N,N-trimethyl-Methanaminium
  • 1-Carboxy-N,N,N-trimethyl-Methanaminium hydroxide
  • 1-carboxy-N,N,N-trimethylmethanaminium inner salt
  • 2-(trimethylazaniumyl)acetate
  • 2-N,N,N-trimethylammonio acetate
  • 2-trimethylammonioacetate
  • 2-trimethylammonioethanoate
  • Bet
  • Ektasolve EE
  • Loramine AMB-13
  • Lycine
  • N,N,N-trimethylammonioacetate
  • Trimethylaminoacetic acid
  • Trimethylammonioacetate
  • Trimethylbetaine Glycine
  • a-Earleine
  • acidol
  • alpha-Earleine
  • 11042-12-9
  • 24980-93-6
  • 45631-77-4
  • 590-30-7

Applications:

HILIC Separation of Carboxymethylcysteine and Betaine

August 22, 2008

In this HPLC method, betaine and carboxymethylcysteine are separated by HILIC mixed-mode mechanism. Betaine and carboxymethylcysteine are very hydrophilic compounds which are not retained on reverse phase columns. Compounds are separated by combination of HILIC and ion-exchange mechanisms. In HIILIC mode, Obelisc N columns allow operating at lower organic concentration for improved solubility of analytes. Method can be used for quantitative or qualitative analysis of betaine and carboxymethylcysteine using ESLD or LC/MS detection. Betaine in chemistry is any neutral chemical compound with a positively charged cationic functional group such as ammonium ion or phosphonium ion (generally: onium ions) which bears no hydrogen atom and with a negatively charged functional group such as a carboxylate group which may not be adjacent to the cationic site. Historically the term was reserved for tetramethylglycine only.

Application Column

Obelisc N

SIELC has developed the Obelisc™ columns, which are mixed-mode and utilize Liquid Separation Cell technology (LiSC™). These cost-effective columns are the first of their kind to be commercially available and can replace multiple HPLC columns, including reversed-phase (RP), AQ-type reversed-phase, polar-embedded group RP columns, normal-phase, cation-exchange, anion-exchange, ion-exclusion, and HILIC (Hydrophilic Interaction Liquid Chromatography) columns. By controlling just three orthogonal method parameters - buffer concentration, buffer pH, and organic modifier concentration - users can adjust the column properties with pinpoint precision to separate complex mixtures.

Select options
Application Analytes:
Betaine
Carboxymethylcysteine
Application Detection:
ELSD Detection
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Retention Characteristics of Betaine in Mixed-Mode HPLC

May 5, 2005

HPLC Application: Retention Characteristics of Betaine in Mixed-Mode HPLC

The retention of the zwitterion betaine on Primesep 200 demonstrates the tunability of Primesep columns. Retention of betaine is altered by acid type, amount of acid in the mobile phase, and the amount of organic solvent. Typical reversed-phase columns do not show this tunability with simple mass spec compatible mobile phases of water, acetonitrile (MeCN, ACN) and trifluoracetic acid (TFA) with evaporative light scattering detection (ELSD).

Application Column

Primesep 200

The Primesep family of mixed-mode columns offers a wide variety of stationary phases, boasting unprecedented selectivity in the separation of a broad array of chemical compounds across multiple applications. Corresponding Primesep guard columns, available with all stationary phases, do not require holders. SIELC provides a method development service available to all customers. Inquire about our specially-tailored custom LC-phases for specific separations.

Select options
Application Analytes:
Betaine
Quaternary Amines
Zwitterion
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.