Prothoate

Prothoate structural formula

CAS Number2275-18-5
Molecular FormulaC9H20NO3PS2
Molecular Weight285.360
InChI KeyQTXHFDHVLBDJIO-UHFFFAOYSA-N
LogP2.43
Synonyms
  • Prothoate
  • O,O-Diethyl S-{2-oxo-2-[(propan-2-yl)amino]ethyl} phosphorodithioate
  • Phosphorodithioic acid, O,O-diethyl S-[2-[(1-methylethyl)amino]-2-oxoethyl] ester
  • 2275-18-5
  • Acetamide, N-isopropyl-2-mercapto-, S-ester with O,O-diethyl phosphorodithioate
  • American cyanamid 18682
  • BRN 1794477
  • Caswell No. 344B
  • 2-Diethoxyphosphinothioylthio-N-isopropylacetamide
  • O,O-Diethyl S-(N-isopropylcarbamoylmethyl) dithiophosphate
  • O,O-Diethyl S-isopropylcarbamoylmethyl phosphorodithioate
  • O,O-Diethyl S-(N-isopropylcarbamoylmethyl) phosphorodithioate
  • O,O-Diethyl S-(2-((1-methylethyl)amino)-2-oxoethyl) phosphorodithioate
  • O,O-Diethyl phosphorodithioate S-ester with N-isopropyl-2-mercaptoacetamide
  • O,O-Diethyl phosphorodithioate S-ester with N-2-isopropyl-2-mercaptoacetamide
  • O,O-Diethyldithiophosphorylacetic acid, N-monoisopropylamide
  • EINECS 218-893-2
  • EPA Pesticide Chemical Code 344300
  • Fostion
  • Isopropyl diethyldithiophosphorylacetamide
  • N-Monoisopropylamide of O,O-diethyldithiophosphorylacetic acid
  • Oleofac
  • Prothoat
  • Protoat
  • Telefos
  • UNII-4V035A5L4B

Applications:

Separation of Prothoate on Newcrom R1 HPLC column

May 16, 2018
Separation of Prothoate on Newcrom R1 HPLC column

Prothoate can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

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Application Analytes:
Prothoate
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.