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The Promix family of mixed-mode columns offer an alternative chromatography technology to deliver efficient resolution of peptides and proteins. The technology is based on a combination of both hydrophobic and ionic interactions. This approach is possible due to a new type of separation media: a chemical combination of hydrophobic and ionic functional groups on a ligand bonded to a silica support. With this phase, unparalleled selectivity and peak capacity can be achieved. Independent adjustment of the amount of buffer and organic modifier creates an infinite number of separation conditions that are suitable for many types of bio-molecules.

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