N-Nitro-L-arginine

N-Nitro-L-arginine structural formula

CAS Number2149-70-4
Molecular FormulaC6H13N5O4
Molecular Weight219.202
InChI KeyMRAUNPAHJZDYCK-BYPYZUCNSA-N
LogP-2.37
Synonyms
  • N-Nitro-L-arginine
  • N5-(N-Nitrocarbamimidoyl)-L-ornithine
  • L-Ornithine, N5-[imino(nitroamino)methyl]-
  • 2149-70-4
  • L-NNA
  • L-Ornithine, N5-[imino(nitroamino)methyl]-
  • (+)-NG-Nitroarginine
  • L-Arginine, NG-nitro-
  • L-Arginine, ?-nitro-
  • L-NG-Nitroarginine
  • L-NOARG
  • NG-Nitroarginine
  • NG-Nitro-L-arginine
  • Nitroarginine
  • Nitro-L-arginine
  • NSC 53662
  • N?-Nitro-L-arginin
  • N?-nitro-L-arginina
  • N?-Nitro-L-arginine
  • Ornithine, N5-(nitroamidino)-, L-
  • ?-Nitroarginine
  • ?-Nitro-L-arginine
  • Arginine, omega-nitro-
  • Arginine, omega-nitro-, L-
  • Arginine, N(G)-nitro-
  • EINECS 218-418-9
  • N(G)-Methyl-L-arginine
  • omega-Nitroarginine
  • N(G)-Nitroarginine
  • N(G)-Nitro-L-arginine
  • Norvaline, 5-(2-nitroguanidino)-, (+)-
  • Ornithine, N(5)-(nitroamidino)-, L-
  • N(sup G)-Nitro-L-arginine
  • UNII-7O8V7H6P2J
  • 126265-23-4
  • 13855-78-2
  • 38733-00-5

Applications:

HPLC Method for Analysis of L-Lysine and L-Arginine

February 28, 2018

HPLC Method for Lysine, D-Lysine, Arginine, N-Nitro-L-arginine on Obelisc R by SIELC Technologies

l-Lysine , L-Arginine Chr_1106

High Performance Liquid Chromatography (HPLC) Method for Analysis of Lysine, D-Lysine, Arginine, N-Nitro-L-arginine

L-Lysine is an essential amino acid required for growth and tissue repair, it can also help with anxiety. The amino acid is most often found in red meats,beans, fish, and dairy products. L-Arginine is an essential amino acid that is used to treat congestive heart failure, combat fatigue and circulatory diseases. It is also used to stimulate the immune system. Obelisc R is a reverse-phase column. It contains embedded ionic groups and can retain L-Lysine and L-Arginine. The method is UV compatible and can be used as a general approach for analyzing similar compounds.

Condition
Column Obelisc R, 4.6 x 150 mm, 5 µm, 100 A, dual ended
Mobile Phase MeCN/H2O – 10/90%
Buffer Na2HPO4 pH 6.0 – 25 mM
Flow Rate 1.0 ml/min
Detection UV, 210 nm

Description
Class of Compounds
 Drug, Acid, Hydrophilic, Ionizable, Vitamin, Supplements, Amino acid
Analyzing Compounds Lysine, D-Lysine, Arginine, N-Nitro-L-arginine

Application Column

Obelisc R

Column Diameter: 4.6 mm
Column Length: 150 mm
Particle Size: 5 µm
Pore Size: 100 A
Column options: dual ended

Add to cart
Application Analytes:
Arginine
D-Lysine
Lysine
N-Nitro-L-arginine
Application Detection:
UV Detection
SIELC Technologies usually develops more than one method for each compound. Therefore, this particular method may not be the best available method from our portfolio for your specific application. Before you decide to implement this method in your research, please send us an email to research@sielc.com so we can ensure you get optimal results for your compound/s of interest.

Separation of N-Nitro-L-arginine on Newcrom R1 HPLC column

February 16, 2018
Separation of N-Nitro-L-arginine on Newcrom C18 HPLC column

N-Nitro-L-arginine can be analyzed by this reverse phase (RP) HPLC method with simple conditions. The mobile phase contains an acetonitrile (MeCN), water, and phosphoric acid. For Mass-Spec (MS) compatible applications the phosphoric acid needs to be replaced with formic acid. Smaller 3 µm particles columns available for fast UPLC applications. This liquid chromatography method is scalable and can be used for isolation impurities in preparative separation. It also suitable for pharmacokinetics.

Application Column

Newcrom R1

The Newcrom columns are a family of reverse-phase-based columns. Newcrom A, AH, B, and BH are all mixed-mode columns with either positive or negative ion-pairing groups attached to either short (25 Å) or long (100 Å) ligand chains. Newcrom R1 is a special reverse-phase column with low silanol activity.

Select options
Application Analytes:
N-Nitro-L-arginine
The result was obtained by a proprietary SIELC algorithm. It may deviate from the actual experimental data. The experimental data are available upon request. Contact us before ordering the column as there may be a more suitable column alternative by either e-mail: support@sielc.com or by phone: 847-229-2629.